Evidence map›Paper›PMID 35386818›Full record

ArticleBioactive materials2022

Robust genome and RNA editing via CRISPR nucleases in PiggyBac systems.

Yuqian Jiang, Rachel Catherine Hoenisch, Yun Chang, Xiaoping Bao, Craig E Cameron, Xiaojun Lance Lian

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Insights Gained from RNA Editing Targeted by the CRISPR-Cas13 Family.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yuqian JiangDepartment of Biomedical Engineering, Pennsylvania State University, University Park, PA, 16802, USA.
Rachel Catherine HoenischDepartment of Biomedical Engineering, Pennsylvania State University, University Park, PA, 16802, USA.
Yun ChangDavidson School of Chemical Engineering, Purdue University, West Lafayette, IN, 47907, USA.
Xiaoping BaoDavidson School of Chemical Engineering, Purdue University, West Lafayette, IN, 47907, USA.
Craig E CameronDepartment of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA.
Xiaojun Lance LianDepartment of Biomedical Engineering, Pennsylvania State University, University Park, PA, 16802, USA.
Pennsylvania State University · USPurdue University West Lafayette · USUniversity of North Carolina at Chapel Hill · US

Funding

Stem cell immunoengineering for universal cardiac therapy via CRISPR-Cas9R21EB026035 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI LIAN, XIAOJUN · 2018 to 2020
$567k
ModRNA-based Direct Programming of Universal Donor hiPSCs into Immune Evasive Beta CellsR56DK133147 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI LIAN, XIAOJUN · 2023 to 2024
$465k
Contribution of IL-32 gene expression to viral persistenceR21AI149312 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CAMERON, CRAIG E. · 2020 to 2021
$432k
NIAID NIH HHS R21 AI149312NIBIB NIH HHS R21 EB026035NIDDK NIH HHS R56 DK133147
6 · The paper itself

Abstract

CRISPR/Cas-mediated genome editing in human pluripotent stem cells (hPSCs) offers unprecedented opportunities for developing

Indexed as

Cas13dCRISPR-Cas9Genome editingHuman pluripotent stem cellsPiggyBac transposonRNA editing

Identifiers

PMID35386818
PMCPMC8964983
OpenAlexW4210494299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.