ArticleBioactive materials2022
A hydrogel spinal dural patch with potential anti-inflammatory, pain relieving and antibacterial effects.
Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Functionalized bio-patches for intra-abdominal applications.iScience · 2026Review
- Application of hydrogel technologies in the treatment of musculoskeletal disorders.Chinese medical journal · 2026Review
- An Asymmetric Dura-Inspired Collagen Hydrogel Patch with Integrated Dense-Porous Architecture Enabled by Dual-Channel Freeze Casting.Advanced healthcare materials · 2026Article
- A dynamically adaptive wet-adhesive Janus hydrogel patch for sutureless repair of spinal dural defects.Bioactive materials · 2026Article
- A review on thermoresponsive PNIPAM hydrogels for regenerative medicine: from mechanical design to tissue adhesion.Regenerative biomaterials · 2026Review
- Polymer Brush-Based Asymmetric Porous Patch with Excellent Anti-Bacterial and Anti-Contamination Properties Enables Infectious Abdominal Wall Defect Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Bioinspired conductive oriented nanofiber felt with efficient ROS clearance and anti-inflammation for inducing M2 macrophage polarization and accelerating spinal cord injury repair.Bioactive materials · 2025Article
- Designing hydrogel for application in spinal surgery.Materials today. Bio · 2025Review
- A case of pyogenic granuloma and its unique way of management.International journal of surgery case reports · 2025Article
- Liquiritigenin-loaded poly (acrylic acid)-carboxymethyl cellulose hydrogels: formulation optimization, performance evaluation, and assessment of therapeutic efficacy for wound healing and sepsis caused by wound bacterial infection.Frontiers in bioengineering and biotechnology · 2025Article
- Polymeric Dural Biomaterials in Spinal Surgery: A Review.Gels (Basel, Switzerland) · 2024Review
- A low-swelling hydrogel as a multirole sealant for efficient dural defect sealing and prevention of postoperative adhesion.National science review · 2024Article
- Spinal Cord Herniation after Dural Defect Repaired Using Polyglycolic Acid Mesh and Fibrin Glue: A Case Report.Spine surgery and related research · 2023Article
- Recent advance in bioactive hydrogels for repairing spinal cord injury: material design, biofunctional regulation, and applications.Journal of nanobiotechnology · 2023Review
- Clinical management of dural defects: A review.World journal of clinical cases · 2023Review
- Electrospun Nanofibers for Dura Mater Regeneration: A Mini Review on Current Progress.Pharmaceutics · 2023Review
- Application of Single-Cell and Spatial Omics in Musculoskeletal Disorder Research.International journal of molecular sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CSFL caused by spinal dural defect is a common complication of spinal surgery, which need repair such as suture or sealants. However, low intracranial pressure symptoms, wound infection and prolonged hospital associated with pin-hole leakage or loose seal effect were often occurred after surgical suture or sealants repair. Stable, pressure resistance and high viscosity spinal dural repair patch in wet environment without suture or sealants was highly needed. Herein, a bioactive patch composed of alginate and polyacrylamide hydrogel matrix cross-linked by calcium ions, and chitosan adhesive was proposed. This fabricated patch exhibits the capabilities of promoting defect closure and good tight seal ability with the bursting pressure is more than 790 mm H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.