Evidence map›Paper›PMID 35386740›Full record

ReviewJournal of scleroderma and related disorders2021

The role of ultrasound in systemic sclerosis: On the cutting edge to foster clinical and research advancement.

Michael Hughes, Cosimo Bruni, Giovanna Cuomo, Andrea Delle Sedie, Luna Gargani, Marwin Gutierrez, Gemma Lepri, Barbara Ruaro, Tania Santiago, Yossra Suliman and 4 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of scleroderma and related disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Exploring sarcoidosis via nailfold capillaroscopy: A window into the disease's microvascular landscape.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Cardiac sarcoidosis recurrence post-heart transplant: A critical literature and case report.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  11. High-Frequency Ultrasonography in Cutaneous Lupus Erythematosus.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 7 countries.

Michael HughesDepartment of Rheumatology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.ORCID https://orcid.org/0000-0003-3361-4909
Cosimo BruniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Giovanna CuomoDepartment of Medicine of Precision, University of Naples L. Vanvitelli, Naples, Italy.
Andrea Delle SedieRheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID https://orcid.org/0000-0002-7379-4732
Luna GarganiInstitute of Clinical Physiology, National Research Council, Pisa, Italy.
Marwin GutierrezDivision of Musculoskeletal and Rheumatic Diseases, National Institute of Rehabilitation, Mexico City, Mexico.
Gemma LepriDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Barbara RuaroPulmonology Department, University Hospital of Cattinara, Trieste, Italy.
Tania SantiagoRheumatology Department, Centro Hospitalar e Universitáro de Coimbra, Coimbra, Portugal.ORCID https://orcid.org/0000-0002-1562-4022
Yossra SulimanRheumatology and Rehabilitation Department, Assiut University Hospital, Assiut, Egypt.ORCID https://orcid.org/0000-0003-2919-1966
Shinji WatanabeDepartment of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan.
Annamaria IagnoccoAcademic Rheumatology Centre, Università degli Studi di Torino, Turin, Italy.
Daniel FurstDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Silvia Bellando-RandoneDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
University of Florence · ITAssiut University · EGAzienda Ospedaliero-Universitaria Careggi · ITHospitais da Universidade de Coimbra · PTInstituto Nacional de Rehabilitación · MXIstituto di Fisiologia Clinica · ITNippon Medical School · JPOspedale di Cattinara · ITRoyal Hallamshire Hospital · GBUniversity of California, Los Angeles · USUniversity of Pisa · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound has been widely explored in systemic sclerosis in the clinical and research settings. Ultrasound allows a non-invasive and ionising radiation-free 'window' into this complex disease and is well-suited to repeated examinations. Ultrasound provides novel insights into the pathogenesis and measurement of disease in systemic sclerosis, including early (preclinical) internal organ involvement. The purpose of this review is to describe the role of ultrasound to foster clinical and research advancements in systemic sclerosis relating to (1) musculoskeletal, (2) digital ulcer, (3) lung disease and (4) skin disease. We also highlight unmet needs which much be addressed for ultrasound to assume a central role in systemic sclerosis clinical care and research.

Indexed as

digital ulcerlungmusculoskeletalsclerodermaskinSystemic sclerosisultrasound

Identifiers

PMID35386740
PMCPMC8892934
OpenAlexW3103416721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.