Evidence map›Paper›PMID 35386456›Full record

ArticleBioactive materials2022

Proteomics as a tool to gain next level insights into photo-crosslinkable biopolymer modifications.

Nele Pien, Fabrice Bray, Tom Gheysens, Liesbeth Tytgat, Christian Rolando, Diego Mantovani, Peter Dubruel, Sandra Van Vlierberghe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. GelMA synthesis and sources comparison for 3D multimaterial bioprinting.Frontiers in bioengineering and biotechnology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nele PienGhent University, Polymer Chemistry and Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Krijgslaan 281 S4bis, 9000 Gent, Belgium.
Fabrice BrayUniv. Lille, CNRS, USR 3290, MSAP, Miniaturisation pour la Synthèse l'Analyse et la Protéomique, F-59 000, Lille, France.
Tom GheysensGhent University, Polymer Chemistry and Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Krijgslaan 281 S4bis, 9000 Gent, Belgium.
Liesbeth TytgatGhent University, Polymer Chemistry and Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Krijgslaan 281 S4bis, 9000 Gent, Belgium.
Christian RolandoUniv. Lille, CNRS, USR 3290, MSAP, Miniaturisation pour la Synthèse l'Analyse et la Protéomique, F-59 000, Lille, France.
Diego MantovaniLaval University, Laboratory for Biomaterials and Bioengineering, CRC-I, Pavillon Pouliot, Québec G1V 0A6, Canada.
Peter DubruelGhent University, Polymer Chemistry and Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Krijgslaan 281 S4bis, 9000 Gent, Belgium.
Sandra Van VlierbergheGhent University, Polymer Chemistry and Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Krijgslaan 281 S4bis, 9000 Gent, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The distribution of photo-crosslinkable moieties onto a protein backbone can affect a biomaterial's crosslinking behavior, and therefore also its mechanical and biological properties. A profound insight in this respect is essential for biomaterials exploited in tissue engineering and regenerative medicine. In the present work, photo-crosslinkable moieties have been introduced on the primary amine groups of: (i) a recombinant collagen peptide (RCPhC1) with a known amino acid (AA) sequence, and (ii) bovine skin collagen (COL BS) with an unknown AA sequence. The degree of substitution (DS) was quantified with two conventional techniques: an

Indexed as

Biomaterial characterizationChemical modificationsLocalization of functionalizations(Photo-crosslinkable) biomaterialsProteomics

Identifiers

PMID35386456
PMCPMC8965084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.