Evidence map›Paper›PMID 35386449›Full record

ArticleBioactive materials2022

Biocompatibility and degradation comparisons of four biodegradable copolymeric osteosynthesis systems used in maxillofacial surgery: A goat model with four years follow-up.

Barzi Gareb, Nico B van Bakelen, Léon Driessen, Pieter Buma, Jeroen Kuipers, Dirk W Grijpma, Arjan Vissink, Ruud R M Bos, Baucke van Minnen

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Barzi GarebUniversity of Groningen, University Medical Center Groningen, Department of Oral and Maxillofacial Surgery, Hanzeplein 1, 9713 GZ, P.O. Box 30001, 9700 RB, Groningen, the Netherlands.
Nico B van BakelenUniversity of Groningen, University Medical Center Groningen, Department of Oral and Maxillofacial Surgery, Hanzeplein 1, 9713 GZ, P.O. Box 30001, 9700 RB, Groningen, the Netherlands.
Léon DriessenRadboud University Medical Center, Radboud Institute for Molecular Life Sciences, Orthopaedic Research Lab, Houtlaan 4, 6525 XZ, P.O. Box 9102, 6500 HC, Nijmegen, the Netherlands.
Pieter BumaRadboud University Medical Center, Radboud Institute for Molecular Life Sciences, Orthopaedic Research Lab, Houtlaan 4, 6525 XZ, P.O. Box 9102, 6500 HC, Nijmegen, the Netherlands.
Jeroen KuipersUniversity of Groningen, University Medical Center Groningen, Department of Biomedical Sciences of Cells and Systems, Hanzeplein 1, 9713 GZ, P.O. Box 30001, 9700 RB, Groningen, the Netherlands.
Dirk W GrijpmaUniversity of Twente, TechMed Centre, Department of Biomaterials Science and Technology, Drienerlolaan 5, 7522 NB, P.O. Box 217, 7500 AE, Enschede, the Netherlands.
Arjan VissinkUniversity of Groningen, University Medical Center Groningen, Department of Oral and Maxillofacial Surgery, Hanzeplein 1, 9713 GZ, P.O. Box 30001, 9700 RB, Groningen, the Netherlands.
Ruud R M BosUniversity of Groningen, University Medical Center Groningen, Department of Oral and Maxillofacial Surgery, Hanzeplein 1, 9713 GZ, P.O. Box 30001, 9700 RB, Groningen, the Netherlands.
Baucke van MinnenUniversity of Groningen, University Medical Center Groningen, Department of Oral and Maxillofacial Surgery, Hanzeplein 1, 9713 GZ, P.O. Box 30001, 9700 RB, Groningen, the Netherlands.
University Medical Center Groningen · NLRadboud University Nijmegen · NLUniversity of Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Applying biodegradable osteosyntheses avoids the disadvantages of titanium osteosyntheses. However, foreign-body reactions remain a major concern and evidence of complete resorption is lacking. This study compared the physico-chemical properties, histological response and radiographs of four copolymeric biodegradable osteosynthesis systems in a goat model with 48-months follow-up. The systems were implanted subperiosteally in both tibia and radius of 12 Dutch White goats. The BioSorb FX [poly(70LLA-

Indexed as

Absorbable implantsBiocompatible materialsFracture fixationOrthopaedic fixation devicesPolymersReconstructive surgical procedures

Identifiers

PMID35386449
PMCPMC8961280
OpenAlexW4205570888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.