ArticleArchive of applied mechanics = Ingenieur-Archiv2022
A multiphasic model for determination of water and solute transport across the arterial wall: effects of elastic fiber defects.
Article in Archive of applied mechanics = Ingenieur-Archiv, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- Atherosclerosis increases adventitial pressure and limits solute transport via fluid-balance mechanisms.Biomechanics and modeling in mechanobiology · 2025Article
- Transport Properties of Self-Assembling G-Hydrogels: Evidence for a Tunable Fickian Diffusivity.The journal of physical chemistry. B · 2025Article
- Transport across the thoracic aortic wall: implications for aneurysm pathobiology, diagnosis, and treatment.American journal of physiology. Heart and circulatory physiology · 2025Review
- A multiphasic model for determination of mouse ascending thoracic aorta mass transport properties with and without aneurysm.Biomechanics and modeling in mechanobiology · 2025Article
- Interstitial flow, pressure and residual stress in the aging carotid artery model in FEBio.Biomechanics and modeling in mechanobiology · 2024Article
- Changes in transmural mass transport correlate with ascending thoracic aortic aneurysm diameter in a fibulin-4 E57K knockin mouse model.American journal of physiology. Heart and circulatory physiology · 2023Article
- Pentagalloyl Glucose (PGG) Prevents and Restores Mechanical Changes Caused by Elastic Fiber Fragmentation in the Mouse Ascending Aorta.Annals of biomedical engineering · 2023Article
- Increases in hydraulic conductance and solute permeability in a mouse model of ascending thoracic aortic aneurysm.Journal of biomechanics · 2022Article
- Hydraulic permeability and compressive properties of porcine and human synovium.Biophysical journal · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Transport of solute across the arterial wall is a process driven by both convection and diffusion. In disease, the elastic fibers in the arterial wall are disrupted and lead to altered fluid and mass transport kinetics. A computational mixture model was used to numerically match previously published data of fluid and solute permeation experiments in groups of mouse arteries with genetic (knockout of fibulin-5) or chemical (treatment with elastase) disruption of elastic fibers. A biphasic model of fluid permeation indicated the governing property to be the hydraulic permeability, which was estimated to be 1.52×10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.