ArticleReproductive medicine and biology
Histopathological evaluation of cesarean scar defect in women with cesarean scar syndrome.
Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Impact of previous cesarean delivery on reproductive outcomes of assisted reproductive technology: a Bayesian network meta-analysis.Annals of medicine · 2025Pooled it
- Exploring uterine niche: a systemic review on secondary infertility rates, pathophysiological correlations, impact on assisted reproduction technology (ART), and the efficacy of surgical interventions.BMC pregnancy and childbirth · 2025Pooled it
- Cesarean scar dehiscence in early puerperium and influence of barbed suture: tridimensional ultrasound evaluation in a randomized clinical study.Acta cirurgica brasileira · 2024Trial
- Prostaglandin E2-mediated aging microenvironment fuels pathogenic fibrosis in cesarean section scar defect.EMBO molecular medicine · 2026Article
- Prediction of preterm birth using 3D volume cesarean scar morphology in pregnant women with previous advanced labor cesarean delivery.Acta obstetricia et gynecologica Scandinavica · 2026Observational
- Ultrasound-guided bladder localization for predicting abdominal adhesions, bladder injury, and scar healing in repeat cesarean sections: a prospective cohort study.International urology and nephrology · 2026Article
- A Case of Term Delivery After Cervical Cerclage Following Hysteroscopic and Laparoscopic Uterine Scar Repair for Cesarean Scar Disorder.The journal of obstetrics and gynaecology research · 2026Article
- Clinical Outcomes of Laparoscopic Folding Suture for Cesarean Scar Defect and Its Impact on Pregnancy Outcomes: A Retrospective Study.International journal of women's health · 2026Article
- A Rare Case of Cesarean Scar Diverticulum Rupture Induced by Intrauterine Infection in a Non-Pregnant Woman.International medical case reports journal · 2026Article
- Comparison of the effectiveness and pregnancy outcomes of the "incise and suture" versus "fold and suture" methods in hysteroscopic-assisted laparoscopic treatment of previous cesarean scar defect: A retrospective cohort study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Article
- Robotic-assisted laparoscopic niche repair (RALNR): technique development and pregnancy-associated outcomes.Journal of robotic surgery · 2025Article
- High Risk of Chronic Endometritis in Isthmocele-A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Caesarean Scar Endometrial Defects Contribute to Post-Caesarean Abnormal Uterine Bleeding and Chronic Endometritis: A Retrospective Case-Control Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Hematometra within a cesarean scar defect in a perimenopausal woman: A case report.The journal of obstetrics and gynaecology research · 2025Article
- Development and validation of a nomogram model for predicting postoperative complications of cesarean scar pregnancy based on clinical data.Frontiers in medicine · 2025Article
- Pregnancy outcomes in women with cesarean section scar defects and secondary infertility after vaginal repair: a multicenter observational cohort analysis.Frontiers in medicine · 2025Article
- Scar matrix drives Piezo1 mediated stromal inflammation leading to placenta accreta spectrum.Nature communications · 2024Article
- The association between gynecological complaints and the uterine sonographic features in women with a history of cesarean section.Archives of gynecology and obstetrics · 2024Article
- Isthmoceles - Accuracy of imaging diagnosis and clinical correlation with histology: A prospective cohort study.Facts, views & vision in ObGyn · 2024Article
- Impact of cesarean scar defect on reproductive outcomes after assisted reproductive technology.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To explore the histopathological findings of cesarean scar defect (CSD) and the immunological component in women with cesarean scar syndrome (CSS). Methods: This retrospective study was conducted in a university hospital and a public hospital. A total of 63 patients with secondary infertility due to CSS who underwent laparoscopic resection of the CSD lesion were enrolled (CSS group), and 21 patients who underwent hysterectomy with a history of cesarean section were enrolled as control (non-CSS group). We compared the differences in histopathological findings of CSD lesions by hematoxylin and eosin staining and immunohistochemistry for CD3, CD20, CD56, CD68, CD138, myeloperoxidase, and tryptase between the two groups. Results: The frequency of presence of endometrium on the CSD surface was significantly lower ( Conclusions: This study suggested that the absence of endometrium, presence of adenomyosis, and chronic inflammation in CSD contributes to secondary infertility due to CSS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.