Evidence map›Paper›PMID 35386057›Full record

ArticleArchives of toxicology2022

New aspects in deriving health-based guidance values for bromate in swimming pool water.

C Röhl, M Batke, G Damm, A Freyberger, T Gebel, U Gundert-Remy, J G Hengstler, A Mangerich, A Matthiessen, F Partosch and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 2 countries.

C RöhlInstitute of Toxicology and Pharmacology for Natural Scientists, Christiana Albertina University Kiel, Kiel, Germany. claudia.roehl@gmx.net.ORCID http://orcid.org/0000-0003-2798-2465
M BatkeUniversity Emden/Leer, Emden, Germany.
G DammDepartment of Hepatobiliary Surgery and Visceral Transplantation, University Hospital, Leipzig University, Leipzig, Germany.
A FreybergerResearch and Development, Pharmaceuticals, RED-PCD-TOX-P&PC Clinical Pathology, Bayer AG, Wuppertal, Germany.
T GebelFederal Institute for Occupational Safety and Health (BAuA), Dortmund, Germany.
U Gundert-RemyInstitute for Clinical Pharmacology and Toxicology, Universitätsmedizin Berlin, Charité Berlin, Germany.
J G HengstlerLeibniz Research Centre for Working Environment and Human Factors (IfADo), TU Dortmund University, Dortmund, Germany.
A MangerichMolecular Toxicology, Department of Biology, University of Konstanz, Konstanz, Germany.
A MatthiessenCentral Unit for Environmental Hygiene, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany.
F PartoschDepartment of Toxicology, Fraunhofer-Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany.
T SchuppDepartment of Chemical Engineering, University of Applied Science Muenster, Steinfurt, Germany.
K M WollinFormerly Public Health Agency of Lower Saxony, Hannover, Germany.
H FothInstitute of Environmental Toxicology, University of Halle, Halle/Saale, Germany.
Bayer (Germany) · DECharité - Universitätsmedizin Berlin · DEChristian-Albrechts-Universität zu Kiel · DEFederal Institute for Occupational Safety and Health · DEFH Münster · DEFraunhofer Institute for Toxicology and Experimental Medicine · DETU Dortmund University · DEUniversity Hospital Leipzig · DEUniversity Hospital Schleswig-Holstein · DEUniversity of Applied Sciences Emden Leer · DEUniversity of Konstanz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bromate, classified as a EU CLP 1B carcinogen, is a typical by-product of the disinfection of drinking and swimming pool water. The aim of this study was (a) to provide data on the occurrence of bromate in pool water, (b) to re-evaluate the carcinogenic MOA of bromate in the light of existing data, (c) to assess the possible exposure to bromate via swimming pool water and (d) to inform the derivation of cancer risk-related bromate concentrations in swimming pool water. Measurements from monitoring analysis of 229 samples showed bromate concentrations in seawater pools up to 34 mg/L. A comprehensive non-systematic literature search was done and the quality of the studies on genotoxicity and carcinogenicity was assessed by Klimisch criteria (Klimisch et al., Regul Toxicol Pharmacol 25:1-5, 1997) and SciRAP tool (Beronius et al., J Appl Toxicol, 38:1460-1470, 2018) respectively. Benchmark dose (BMD) modeling was performed using the modeling average mode in BMDS 3.1 and PROAST 66.40, 67 and 69 (human cancer BMDL

Indexed as

NeoplasmsSwimming PoolsWater Pollutants, ChemicalAdultBromatesCarcinogensHumansInfantReproducibility of ResultsSwimmingWaterBromatesCarcinogensWaterWater Pollutants, ChemicalBromateDisinfectionExposureMode of actionRisk assessmentSwimming pool water

Identifiers

PMID35386057
PMCPMC9095538
OpenAlexW4225716611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.