Evidence map›Paper›PMID 35386049›Full record

ArticleClinical rheumatology2022

Reproductive concerns and contributing factors in women of childbearing age with systemic lupus erythematosus.

Xingxin Wang, Jingjing Li, Qian Liang, Xiaowei Ni, Rui Zhao, Ting Fu, Juan Ji, Liren Li, Zhifeng Gu, Chen Dong

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xingxin WangDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, People's Republic of China.
Jingjing LiDepartment of Emergency, Affiliated Hospital of Nantong University, Nantong, 226001, People's Republic of China.
Qian LiangDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, People's Republic of China.
Xiaowei NiDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, People's Republic of China.
Rui ZhaoResearch Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, People's Republic of China.
Ting FuResearch Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, People's Republic of China.
Juan JiDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, People's Republic of China.
Liren LiDepartment of Gastroenterology, Affiliated Hospital of Nantong University, Nantong, 226001, People's Republic of China.
Zhifeng GuDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, People's Republic of China. guzhifeng@126.com.
Chen DongDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, People's Republic of China. dongchensc@126.com.ORCID http://orcid.org/0000-0003-4975-6426
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesReproductive concerns are common in women of childbearing age with systemic lupus erythematosus (SLE) with inadequate disclosure. This study aimed to investigate the contributing factors of reproductive concerns and to evaluate their impact on health-related quality of life.

methodsOne hundred eighty women of childbearing age with SLE were enrolled in this cross-sectional study in Affiliated Hospital of Nantong University from March 2021 to December 2021. A series of questionnaires were conducted: Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), the Hospital Anxiety and Depression Scale (HADS), the Multidimensional Fatigue Inventory (MFI-20), Female Sexual Distress Scale-Revised (FSDS-R), Family Assessment Device (APGAR), the Medical Coping Modes Questionnaire (MCMQ), the Short-Form 36 (SF-36), and the Chinese version of Reproductive Concerns After Cancer (RCAC). Independent t test, one-way ANOVA, Mann-Whitney U test, Pearson/Spearman, and multiple linear stepwise regression were used to analyze the data.

resultsThe results indicated that female SLE patients were more concerned about the child's health and personal health than becoming pregnant, fertility potential, partner disclose and acceptance; SLE patients with the characteristics of living in rural residence, having no reproductive history, fearing unexpected pregnancy, sexual distress, and depression showed more serious fertility concerns. Meanwhile, most female SLE patients adopted active confrontation when facing reproductive concerns, and these patients were significantly lower in the dimension score of mental related quality of life.

conclusionsOur study demonstrated that female SLE patients should be paid more attention to their fertility concerns and effective intervention measures should be carried out to relieve their reproductive concerns, so as to improve their long-term quality of life if their disease condition permits.

Indexed as

Lupus Erythematosus, SystemicQuality of LifeChildCross-Sectional StudiesDepressionFemaleHumansPregnancySeverity of Illness IndexSurveys and QuestionnairesChildbearing ageQuality of lifeReproductive concernsSystemic lupus erythematosus

Identifiers

PMID35386049
OpenAlexW4225879089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.