Evidence map›Paper›PMID 35385161›Full record

ReviewJournal of clinical laboratory analysis2022

RNA-binding proteins in diabetic microangiopathy.

Chao Tu, Liangzhi Wang, Lan Wei

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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  7. RNA-binding proteins in diabetic microangiopathy.Journal of clinical laboratory analysis · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chao TuDepartment of Internal Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Liangzhi WangDepartment of Internal Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Lan WeiDepartment of Internal Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, China.ORCID https://orcid.org/0000-0003-0673-725X
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the most common complication of diabetes, the diabetic microangiopathy characterizes diabetic retinopathy (DR) and nephropathy (DN). Diabetic microangiopathy has always been a serious clinical problem. A wide variety of nucleic acid interacting factors called the RNA binding proteins (RBPS) take part in several crucial cellular processes.

methodsOver the past decade, studies have shown that RBPs have crucial part in both malignant tumors and diabetes, especially in diabetic microangiopathy. This review examined the research history of RBPS in DR and DN.

resultsWe reviewed the literature and found that RBPS is potentially useful as therapeutic targets, diagnostic markers, or predict disease progression.

conclusionHuR acts as a vital therapeutic targeting protein in diabetic microangiopathy. IGF2BP2, P311, TTP, YBX1, and MBNL1 have a potential role in the treatment of DN.

Indexed as

Diabetes Mellitus, Type 2Diabetic AngiopathiesDiabetic NephropathiesDiabetic RetinopathyRNA-Binding ProteinsHumansIGF2BP2 protein, humanRNA-Binding Proteinsdiabetic nephropathydiabetic retinopathynon-coding RNARNA-binding proteins

Identifiers

PMID35385161
PMCPMC9102490
OpenAlexW4226093175

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.