Evidence map›Paper›PMID 35384992›Full record

ArticleRevista do Colegio Brasileiro de Cirurgioes2022

Low serum levels of vitamin D significantly increase the risk of death in older adults with hip fractures: a prospective cohort.

Marcelo Teodoro Ezequiel Guerra, Mario Wagner, Alfonso Vargas, Carlos Roberto Galia

Open access · goldAbstract read
In one paragraph

Article in Revista do Colegio Brasileiro de Cirurgioes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. 25-Hydroxyvitamin D Levels, Free Serum Calcium, Glomerular Filtration Rate, Albumin, and Femoral Fracture Elderly Patient Mortality.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marcelo Teodoro Ezequiel Guerra- Universidade Luterana do Brasil - Canoas - RS - Brasil.ORCID http://orcid.org/0000-0002-1007-4818
Mario Wagner- Universidade Federal do Rio Grande do Sul - Porto Alegre - RS - Brasil.ORCID http://orcid.org/0000-0002-3661-4851
Alfonso Vargas- Universidade Luterana do Brasil - Canoas - RS - Brasil.ORCID http://orcid.org/0000-0002-3916-7970
Carlos Roberto Galia- Universidade Federal do Rio Grande do Sul - Porto Alegre - RS - Brasil.ORCID http://orcid.org/0000-0003-1731-4543
Universidade Federal do Rio Grande do Sul · BRUniversidade Luterana do Brasil · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveto evaluate the relationship between 25(OH)D3 levels and fatal outcome in patients over 60 years of age undergoing surgical repair of hip fractures.

methodsprospective cohort of patients undergoing surgical repair of hip fractures. At admission, 25(OH)D3 levels were measured, among other parameters. Patients were followed for at least 1 year, and incident mortality was recorded.

results209 patients were included in the study, with a mean age of 79.5 ± 7.6 years among survivors and 80.7 ± 8.2 years among those who died in the first postoperative year (p=0.346). The 25(OH)D3 levels of survivors were significantly higher than those of patients who died (p=0.003). After adjusting for confounding variables, 25(OH)D3 levels below 12.5ng/mL were significant risk factors regardless of mortality (adjusted OR: 7.6; 95% CI: 2.35 to 24.56).

conclusionsour data show that serum 25(OH)D3 levels below 12.5ng/mL significantly and independently increased the risk of mortality in the first year after surgical repair of low-energy hip fracture in patients over 60 years of age in the geographic region where this study was conducted. Low albumin also showed a significant association with mortality in these patients. All other factors had no significant associations.

Indexed as

Hip FracturesVitamin D DeficiencyAgedAged, 80 and overCohort StudiesHumansMiddle AgedProspective StudiesRisk FactorsVitamin DVitamin D

Identifiers

PMID35384992
PMCPMC10578824
OpenAlexW4225725350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.