Evidence map›Paper›PMID 35384710›Full record

ArticleMicrobiology spectrum2022

Gut Microbiota and Metabolites in Atrial Fibrillation Patients and Their Changes after Catheter Ablation.

Kang Huang, Yuegang Wang, Yang Bai, Qiuyan Luo, Xuancai Lin, Qiuyu Yang, Shihao Wang, Hongjie Xin

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Association of gut microbiome dysbiosis with the progression of atrial fibrillation: A systematic review.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Pooled it
  5. mBio · 2026
    Article
  6. Review
  7. Correlation Between Dysbiosis and Atrial Fibrillation: What's New?International journal of molecular sciences · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Mendelian Randomization in Atrial Fibrillation.Arquivos brasileiros de cardiologia · 2024
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kang HuangDepartment of Gastroenterology, Nanfang Hospitalgrid.416466.7, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Yuegang WangDepartment of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospitalgrid.416466.7, Southern Medical Universitygrid.284723.8, Guangzhou, China.ORCID 0000-0002-1116-8402
Yang BaiDepartment of Gastroenterology, Nanfang Hospitalgrid.416466.7, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Qiuyan LuoDepartment of Gastroenterology, Nanfang Hospitalgrid.416466.7, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Xuancai LinDepartment of Gastroenterology, Nanfang Hospitalgrid.416466.7, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Qiuyu YangDepartment of Gastroenterology, Nanfang Hospitalgrid.416466.7, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Shihao WangDepartment of Gastroenterology, Nanfang Hospitalgrid.416466.7, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Hongjie XinDepartment of Gastroenterology, Nanfang Hospitalgrid.416466.7, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Nanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota has been shown to be associated with multiple cardiovascular diseases, but there is little research on the gut microbiota and atrial fibrillation (AF); thus, how the gut microbiota and metabolites change in AF patients after catheter ablation is unclear. In this study, we used 16S rRNA high-throughput sequencing and nontargeted metabolomic detection to conduct horizontal and longitudinal analyses of the gut microbiota and metabolites of AF patients. Compared with a control group, species richness and diversity increased significantly in AF patients. Among them, opportunistic pathogenic bacteria, such as Klebsiella, Haemophilus, Streptococcus, and Enterococcus, were significantly increased, and symbiotic bacteria, such as Agathobacter and Butyrivibrio, were significantly reduced. After catheter ablation, intestinal symbiotic bacteria (

Indexed as

Atrial FibrillationCatheter AblationGastrointestinal MicrobiomeBacteriaHumansMetabolomicsRNA, Ribosomal, 16STreatment OutcomeRNA, Ribosomal, 16Satrial fibrillationgut metabolitesgut microbiota

Identifiers

PMID35384710
PMCPMC9045169
OpenAlexW4225109430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.