Evidence map›Paper›PMID 35384638›Full record

ReviewPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2022

Recent advances in nanoparticle-based targeting tactics for antibacterial photodynamic therapy.

Brydie A Thomas-Moore, Carla Arnau Del Valle, Robert A Field, María J Marín

Abstract readReview
In one paragraph

Review in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Photodynamic anti-biofilm PHEMA/Rose Bengal hydrogels enhanced by iodide: evidence for hydrogen peroxide and triiodide formation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Fighting Methicillin-ResistantInternational journal of molecular sciences · 2023
    Review
  13. Review
  14. Article
  15. Precise antibacterial therapeutics based on stimuli-responsive nanomaterials.Frontiers in bioengineering and biotechnology · 2023
    Review
  16. TiOMaterials (Basel, Switzerland) · 2022
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brydie A Thomas-MooreSchool of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK. brydie.thomasmoore@gmail.com.ORCID http://orcid.org/0000-0001-5386-9568
Carla Arnau Del ValleSchool of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.ORCID http://orcid.org/0000-0002-8798-3761
Robert A FieldNorwich Research Park Innovation Centre, Iceni Glycoscience Ltd, Colney Lane, Norwich, NR4 7GJ, UK.ORCID http://orcid.org/0000-0001-8574-0275
María J MarínSchool of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK. m.marin-altaba@uea.ac.uk.ORCID http://orcid.org/0000-0001-8021-5498

Funding

Biotechnology and Biological Sciences Research Council BB/M016609/1
6 · The paper itself

Abstract

The rise of antibacterial drug resistance means treatment options are becoming increasingly limited. We must find ways to tackle these hard-to-treat drug-resistant and biofilm infections. With the lack of new antibacterial drugs (such as antibiotics) reaching the clinics, research has switched focus to exploring alternative strategies. One such strategy is antibacterial photodynamic therapy (aPDT), a system that relies on light, oxygen, and a non-toxic dye (photosensitiser) to generate cytotoxic reactive oxygen species. This technique has already been shown capable of handling both drug-resistant and biofilm infections but has limited clinical approval to date, which is in part due to the low bioavailability and selectivity of hydrophobic photosensitisers. Nanotechnology-based techniques have the potential to address the limitations of current aPDT, as already well-documented in anti-cancer PDT. Here, we review recent advances in nanoparticle-based targeting tactics for aPDT.

Indexed as

Anti-Bacterial AgentsNanoparticlesPhotochemotherapyBiofilmsDrug Delivery SystemsPhotosensitizing AgentsAnti-Bacterial AgentsPhotosensitizing AgentsAntibacterial photodynamic therapyaPDTBacteriaNanoparticlesTargeting

Identifiers

PMID35384638
PMCPMC9287206

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.