Evidence map›Paper›PMID 35384312›Full record

ArticleJournal of the International AIDS Society2022

The question of the question: impactful implementation science to address the HIV epidemic.

Elvin H Geng, Denis Nash, Nittaya Phanuphak, Kimberly Green, Sunil Solomon, Anna Grimsrud, Annette H Sohn, Kenneth H Mayer, Till Bärnighausen, Linda-Gail Bekker

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Fostering citizen-engaged HIV implementation science.Journal of the International AIDS Society · 2024
    Article
  14. Article
  15. Journal of the International AIDS Society · 2024
    Article
  16. Programme Science in PEPFAR: a pathway to a sustainable HIV response.Journal of the International AIDS Society · 2024
    Article
  17. Article
  18. Navigating grey areas in HIV and mental health implementation science.Journal of the International AIDS Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elvin H GengCenter for Dissemination and Implementation, Institute of Public Health, Division of Infectious Diseases, Department of Medicine, School of Medicine at Washington University in St. Louis, St. Louis, Missouri, USA.
Denis NashInstitute for Implementation Science in Population Health, City University of New York, New York, USA.
Nittaya PhanuphakInstitute of HIV Research and Innovation (IHRI), Bangkok, Thailand.
Kimberly GreenPrimary Health Care, PATH, Seattle, Washington, USA.
Sunil SolomonDivision of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Anna GrimsrudInternational AIDS Society, Geneva, Switzerland.
Annette H SohnTREATAsia and amfAR, Bangkok, Thailand.
Kenneth H MayerThe Fenway Institute and Harvard Medical School, Boston, Massachusetts, USA.
Till BärnighausenHeidelberg Institute of Global Health, Faculty of Medicine and University Hospital, Heidelberg, Germany.
Linda-Gail BekkerInstitute of Infectious Disease and Molecular Medicine, Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionQuestions about the implementation of evidence-based intervention to treat and prevent HIV have risen to the top of the field's scientific priorities. Despite the availability of highly efficacious treatment and prevention interventions, impact has fallen short of targets because these interventions are used with insufficient reach, consistency, sustainability and equity in diverse real-world settings. At present, substantial excitement for implementation science - defined as research methods and strategies to improve use of evidence-based interventions - has focused on developing and disseminating methods to conduct rigorous research. Yet, impactful answers depend on a sometimes less visible, but even more important, step: asking good questions about implementation. DISCUSSION: In this commentary, we offer several considerations for researchers formulating implementation research questions based on several distinctive features of the field. First, as findings are used not only by other researchers but by implementers, scientific questions must incorporate a range of stakeholder and community perspectives to be most relevant. Second, real-world settings are contextually diverse, and the most relevant scientific questions must position answers to make sense within these contexts (whether geographical, organizational and sociological), rather than apart from them. Third, implementation is complex and dynamic; consequently, research questions must make use of emerging standards in describing implementation strategies and their effects whenever possible. Finally, the field of implementation science continues to evolve, so framing problems with a diverse disciplinary lens will enable researchers to pose insightful and impactful questions.

conclusionsWe are now at a juncture marked by both rich evidence-based interventions and a persistent global pandemic. To achieve continued scientific progress against the HIV epidemic, asking the right questions might be part of the answer itself.

Indexed as

HIV InfectionsImplementation ScienceHumansPandemicsResearch Personneleffectiveness researchHIVimplementation scienceimplementation strategiespublic healthresearch questions

Identifiers

PMID35384312
PMCPMC8982316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.