Evidence map›Paper›PMID 35384275›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2022

Effect of influenza vaccination in solid organ transplant recipients: A nationwide population-based cohort study.

Zitta Barrella Harboe, Daniel Modin, Finn Gustafsson, Michael Perch, Gunnar Gislason, Søren Schwartz Sørensen, Allan Rasmussen, Tor Biering-Sørensen, Susanne Dam Nielsen

Open access · greenAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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  9. Effect of influenza vaccination in solid organ transplant recipients: A nationwide population-based cohort study.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zitta Barrella HarboeDepartment of Infectious Diseases, Vaccination Clinic for Immunocompromised, University Hospital of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-5552-0095
Daniel ModinDepartment of Cardiology, University of Copenhagen, Herlev & Gentofte Hospital, Copenhagen, Denmark.ORCID 0000-0002-7566-0519
Finn GustafssonDepartment of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-2144-341X
Michael PerchDepartment of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-9740-1246
Gunnar GislasonDepartment of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark.
Søren Schwartz SørensenDepartment of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-5898-8048
Allan RasmussenDepartment of Surgical Gastroenterology, Liver Transplant Unit, University Hospital of Copenhagen, Copenhagen, Denmark.
Tor Biering-SørensenDepartment of Cardiology, University of Copenhagen, Herlev & Gentofte Hospital, Copenhagen, Denmark.ORCID 0000-0003-4209-2778
Susanne Dam NielsenDepartment of Infectious Diseases, Vaccination Clinic for Immunocompromised, University Hospital of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-6391-7455
University of Copenhagen · DKCopenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination can prevent influenza in solid organ transplant (SOT) recipients. Using a modified season-specific approach over nine consecutive influenza seasons, we investigated influenza vaccination coverage and effectiveness in a population-based nationwide cohort study that included all SOT recipients aged ≥18 years who were living in Denmark from December 1, 2007 to April 1, 2016. The primary outcome was the season-specific risk of all-cause pneumonia admission. Secondary outcomes were season-specific influenza-related admission, intensive care unit (ICU) admission, and all-cause mortality. Crude and adjusted hazard ratios (aHRs) with 95% confidence intervals (CIs) were estimated using Cox proportional hazards regression models. In total, 11 381 person-years of follow-up data were collected from 5745 SOT recipients, 48% of whom were vaccinated. Influenza vaccination was associated with a reduced risk of all-cause pneumonia admission (aHR, 0.83; 95% CI, 0.69-0.99; p = .035) and all-cause mortality (aHR, 0.60; 95% CI, 0.47-0.76; p = .001), but not influenza-related admission (aHR, 0.75; 95% CI, 0.46-1.22; p = .24) or ICU admission (aHR, 0.84; 95% CI, 0.67-1.06; p = .14) during the same season. Despite these benefits, uptake of influenza vaccination among SOT recipients was low. Therefore, annual influenza vaccination needs to be prioritized.

Indexed as

Influenza, HumanInfluenza VaccinesOrgan TransplantationTransplant RecipientsAdolescentAdultCohort StudiesHumansPneumoniaVaccinationInfluenza VaccinesInfluenzapneumoniaSOTvaccination

Identifiers

PMID35384275
PMCPMC9790571
OpenAlexW4224090319

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.