Evidence map›Paper›PMID 35384270›Full record

ReviewJournal of cosmetic dermatology2023

In search of the perfect tan: Chemical activity, biological effects, business considerations, and consumer implications of dihydroxyacetone sunless tanning products.

Josh Turner, Danielle A O'Loughlin, Phill Green, Tom O McDonald, Kevin J Hamill

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of cosmetic dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Molecular Targets in Modern Cosmetic Science.Molecules (Basel, Switzerland) · 2026
    Review
  2. Human Keratinocyte Responses to Woodsmoke Chemicals.Chemical research in toxicology · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Josh TurnerInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.
Danielle A O'LoughlinInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.ORCID https://orcid.org/0000-0002-9313-8433
Phill GreenPZ Cussons Manufacturing, Manchester, UK.
Tom O McDonaldDepartment of Chemistry, University of Liverpool, Liverpool, UK.ORCID https://orcid.org/0000-0002-9273-9173
Kevin J HamillInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.ORCID https://orcid.org/0000-0002-7852-1944
University of Liverpool · GBNordson (United Kingdom) · GB

Funding

Innovate UKPZ Cussons (International) LimitedUK Research Institute Knowledge Transfer Partnership
6 · The paper itself

Abstract

As the desire and popularity of a tanned appearance continues, the social effects of UV-free tanning are becoming more important. Dihydroxyacetone (DHA) has seen extensive use as the main tanning agent in sunless tanners. The DHA-induced tan is a result of brown melanoidins formed by a non-enzymatic Maillard reaction between DHA and amino acid species found in the stratum corneum. DHA, thereby, provides a safer route to a tanned appearance compared with exposure to ultraviolet radiation. However, DHA is a highly reactive molecule, posing a multitude of challenges for potential product formulations. With their increased use, the safety considerations of topically applied DHA tanners have been investigated. Many different vehicles have been used for topical delivery of DHA, and they are becoming increasingly multifunctional. This review provides a holistic overview of dihydroxyacetone sunless tanning products.

Indexed as

DihydroxyacetoneUltraviolet RaysAmino AcidsDrug CompoundingEpidermisHumansAmino AcidsDihydroxyacetoneartificial tanningself-tanning productsskin

Identifiers

PMID35384270
PMCPMC10083914
OpenAlexW4224283904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.