ArticleEuropean journal of neurology2022
Predictors of malnutrition risk in neurodegenerative diseases: The role of swallowing function.
Article in European journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 11 citations in OpenAlex.
- Artificial Intelligence-Based Muscle Ultrasound: A Novel Approach to Nutritional Evaluation Beyond Quantity in Neurological Patients.Nutrients · 2026Observational
- Clinical, Social, and Healthcare Factors Associated with Nutritional Status in Amyotrophic Lateral Sclerosis: A Multidimensional Approach.Biomedicines · 2026Article
- Investigating Disordered Eating Behaviours Among Individuals Living With Neurodegenerative Disease: A Scoping Review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026Article
- Dietary restriction as a potential neuroprotective intervention: a narrative review of its impact on neuroinflammation across neurodegenerative diseases and other neurological disorders.Frontiers in nutrition · 2026Review
- Swallowing impairment and aspiration risk in clinically stabilized patients hospitalized for acute respiratory events: a cohort-wide machine-learning analysis with COPD-specific insights.Frontiers in medicine · 2026Article
- Unrevealing the sequence of dysphagia progression in ALS: an event-based, FEES-driven staging approach.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Preserved Thermoregulation in Huntington's Disease: Insights from an Observational Case-Control Study.Movement disorders clinical practice · 2025Observational
- Daily Challenges and Resources of Adults with Chronic Dysphagia: A Qualitative Investigation.Dysphagia · 2025Article
- Article
- Nutrition and Huntington's Disease- A Review of Current Practice and Theory.Current nutrition reports · 2025Review
- Effect of Chin Tuck against Resistance Exercise in Citizens with Oropharyngeal Dysphagia-A Randomised Controlled Study.Geriatrics (Basel, Switzerland) · 2022Article
- Predictors of malnutrition risk in neurodegenerative diseases: The role of swallowing function.European journal of neurology · 2022Article
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeOropharyngeal dysphagia is generally recognized to increase the risk of malnutrition; however, its role in patients with neurodegenerative disease has yet to be determined. This cross-sectional study aimed to investigate the impact of swallowing function on malnutrition risk in patients with neurodegenerative diseases.
methodsPatients with oral nutrition and diagnosis of Huntington disease (HD), Parkinson disease (PD), or amyotrophic lateral sclerosis (ALS) were recruited. Demographic and clinical data were collected. The swallowing assessment included a fiberoptic endoscopic evaluation of swallowing, an oral phase assessment, and a meal observation scored with the Mealtime Assessment Scale (MAS). Malnutrition risk was assessed with the Mini Nutritional Assessment.
resultsOverall, 148 patients were recruited (54 HD, 33 PD, and 61 ALS). One hundred (67.6%) patients were considered at risk of malnutrition. In the multivariate analysis, age ≥ 65 years (odds ratio [OR] = 3.16, p = 0.014), disease severity (moderate vs mild OR = 3.89, severe vs mild OR = 9.71, p = 0.003), number of masticatory cycles (OR = 1.03, p = 0.044), and MAS safety (OR = 1.44, p = 0.016) were significantly associated with malnutrition risk.
conclusionsProlonged oral phase and signs of impaired swallowing safety during meals, together with older age and disease severity, are independent predictors of malnutrition risk in neurodegenerative diseases. This study broadens the focus on dysphagia, stressing the importance of early detection not only of pharyngeal signs, but also of oral phase impairment and meal difficulties through a multidimensional swallowing assessment.
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