Evidence map›Paper›PMID 35383960›Full record

ArticleAlcoholism, clinical and experimental research2022

The 24-hour rhythm in alcohol craving and individual differences in sleep characteristics and alcohol use frequency.

Garrett C Hisler, Sarah L Pedersen, Brant P Hasler

Open access · greenAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Disruption of circadian rhythms promotes alcohol use: a systematic review.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024
    Pooled it
  2. Trial
  3. Article
  4. Who is alcohol cue-reactive? A machine learning approach.Alcohol and alcoholism (Oxford, Oxfordshire) · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Garrett C HislerUniversity of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7099-8417
Sarah L PedersenUniversity of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.
Brant P HaslerUniversity of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-3123-1106
University of Pittsburgh · US

Funding

The Development of Alcohol Use and Abuse in ADHD Adolescents and Young AdultsR37AA011873 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 2008 to 2017
$7.9M
Delayed sleep phase and risk for adolescent substance useR01DA044143 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HASLER, BRANT P. · 2018 to 2022
$2.8M
Positive and negative reinforcement pathways underlying sleep and alcohol use associationsR01AA026249 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HASLER, BRANT P., PEDERSEN, SARAH L · 2018 to 2022
$2.7M
Development of Drug Use and Abuse in ADHD AdolescentsR01DA012414 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PELHAM, WILLIAM E · 2001 to 2012
$2.2M
Disinhibition and Acute Response to Alcohol in European and African AmericansK01AA021135 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PEDERSEN, SARAH L · 2012 to 2016
$760k
ADOLESCENT ALCOHOL ABUSE AND ATTENTION DEFICIT DISORDERK21AA000202 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 1995 to 1999
–
NIAAA NIH HHS K01 AA021135NIAAA NIH HHS K21 AA000202NIAAA NIH HHS R01 AA026249NIAAA NIH HHS R37 AA011873NIDA NIH HHS R01 DA012414NIDA NIH HHS R01 DA044143
6 · The paper itself

Abstract

backgroundEvidence implicates sleep/circadian factors in alcohol use, suggesting the existence of a 24-h rhythm in alcohol craving, which may vary by individual differences in sleep factors and alcohol use frequency. This study sought to (1) replicate prior findings of a 24-h rhythm in alcohol craving, and (2) examine whether individual differences in sleep timing, sleep duration, or alcohol use frequency are related to differences in the timing of the peak of the craving rhythm (i.e., the acrophase) or magnitude of fluctuation of the rhythm (i.e., amplitude). Finally, whether such associations varied by sex or racial identity was explored.

methodsTwo-hundred fifteen adult drinkers (21 to 35 years of age, 72% male, 66% self-identified as White) completed a baseline assessment of alcohol use frequency and then smartphone reports of alcohol craving intensity six times a day across 10 days. Sleep timing was also recorded each morning of the 10-day period. Multilevel cosinor analysis was used to test the presence of a 24-h rhythm and to estimate acrophase and amplitude.

resultsMultilevel cosinor analysis revealed a 24-h rhythm in alcohol craving. Individual differences in sleep timing or sleep duration did not predict rhythm acrophase or amplitude. However, alcohol use frequency moderated this rhythm wherein individuals who used alcohol more frequently in the 30 days prior to beginning the study had higher mean levels of craving and greater rhythm amplitudes (i.e., greater rhythmic fluctuations). Associations did not vary by sex or racial identity.

conclusionsResults show that alcohol craving exhibits a systematic rhythm over the course of the 24 h and that the frequency of alcohol use may be relevant to the shape of this rhythm. Consideration of daily rhythms in alcohol craving may further our understanding of the mechanisms that drive alcohol use.

Indexed as

CravingIndividualityAdultAlcohol DrinkingCircadian RhythmFemaleHumansMaleSleepSmartphonealcoholcircadian rhythmdiurnal rhythmecological momentary assessmentsleep

Identifiers

PMID35383960
PMCPMC9246905
OpenAlexW4223959455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.