Evidence map›Paper›PMID 35383532›Full record

ArticleBioengineered2022

Novel dual glucagon-like peptide-1/ glucose-dependent insulinotropic polypeptide receptor agonist attenuates diabetes and myocardial injury through inhibiting hyperglycemia, inflammation and oxidative stress in rodent animals.

Ying Wang, Fei Cai, Gang Li, Yong Tao

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. The role of the incretin GIP in inflammation.Journal of endocrinological investigation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ying WangDepartment of Cardiology, Nantong Third People's Hospital and the Third People's Hospital Affiliated to Nantong University, Nantong, People's Republic of China.
Fei CaiDepartment of Cardiology, Nantong Third People's Hospital and the Third People's Hospital Affiliated to Nantong University, Nantong, People's Republic of China.
Gang LiDepartment of Cardiology, Nantong Third People's Hospital and the Third People's Hospital Affiliated to Nantong University, Nantong, People's Republic of China.
Yong TaoDepartment of Intensive Care Unit, Tumor Hospital Affiliated to Nantong University, Nantong Tumor Hospital, Nantong, People's Republic of China.
Wuxi Third People's Hospital · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was aimed to evaluate the therapeutic effects and potent mechanisms of a novel GLP-1/GIP dual agonist on hyperglycemia and myocardial injury in diabetic mice. Novel dual-receptor agonists were designed and then evaluated via

Indexed as

Diabetes Mellitus, ExperimentalHyperglycemiaAnimalsGlucagon-Like Peptide 1InflammationMiceOxidative StressPhosphatidylinositol 3-KinasesReceptors, Gastrointestinal HormoneRodentiagastric inhibitory polypeptide receptorGlucagon-Like Peptide 1Phosphatidylinositol 3-KinasesReceptors, Gastrointestinal Hormoneapoptosisdiabetic cardiomyopathyDual GLP-1/GIP receptor agonistinflammationmouse modeloxidative stress

Identifiers

PMID35383532
PMCPMC9161981
OpenAlexW4224293779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.