Evidence map›Paper›PMID 35383233›Full record

ArticleScientific reports2022

Fusion of fully integrated analog machine learning classifier with electronic medical records for real-time prediction of sepsis onset.

Sudarsan Sadasivuni, Monjoy Saha, Neal Bhatia, Imon Banerjee, Arindam Sanyal

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07163767 (Acute Myocardial Infarction Prediction Using Artificial Intelligence Applied to Electrocardiogram Images), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07163767 active not recruitingnot on this mapstarted 2025, after this paper: background citation

Acute Myocardial Infarction Prediction Using Artificial Intelligence Applied to Electrocardiogram Images

TypeobservationalSponsorGuangdong Provincial People's HospitalRan2025 to 2028Enrolled150,000ConditionsAcute Myocardial Infarction (AMI), Electrocardiography, Artifical IntelligenceArmsDeep learning approach of ECG for AMI detection
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  7. Machine Learning and Deep Learning Models for Early Sepsis Prediction: A Scoping Review.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sudarsan Sadasivuni *Electrical Engineering, University at Buffalo, Buffalo, NY, 14260, USA.
Monjoy Saha *Department of Biomedical Informatics, Emory University, Atlanta, GA, 30322, USA.
Neal BhatiaDivision of Cardiology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Imon BanerjeeDepartment of Biomedical Informatics, Emory University, Atlanta, GA, 30322, USA.
Arindam SanyalElectrical Engineering, University at Buffalo, Buffalo, NY, 14260, USA. arindams@buffalo.edu.
Emory University · USUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this work is to develop a fusion artificial intelligence (AI) model that combines patient electronic medical record (EMR) and physiological sensor data to accurately predict early risk of sepsis. The fusion AI model has two components-an on-chip AI model that continuously analyzes patient electrocardiogram (ECG) data and a cloud AI model that combines EMR and prediction scores from on-chip AI model to predict fusion sepsis onset score. The on-chip AI model is designed using analog circuits for sepsis prediction with high energy efficiency for integration with resource constrained wearable device. Combination of EMR and sensor physiological data improves prediction performance compared to EMR or physiological data alone, and the late fusion model has an accuracy of 93% in predicting sepsis 4 h before onset. The key differentiation of this work over existing sepsis prediction literature is the use of single modality patient vital (ECG) and simple demographic information, instead of comprehensive laboratory test results and multiple vital signs. Such simple configuration and high accuracy makes our solution favorable for real-time, at-home use for self-monitoring.

Indexed as

Artificial IntelligenceSepsisElectronic Health RecordsHumansMachine LearningVital Signs

Identifiers

PMID35383233
PMCPMC8983688
OpenAlexW4225754783

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.