Evidence map›Paper›PMID 35383113›Full record

ArticleJournal for immunotherapy of cancer2022

Characterization of the treatment-naive immune microenvironment in melanoma with

Minyu Wang, Soroor Zadeh, Angela Pizzolla, Kevin Thia, David E Gyorki, Grant A McArthur, Richard A Scolyer, Georgina Long, James S Wilmott, Miles C Andrews and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. BRAF mutation and tumor immune microenvironment in new era.American journal of cancer research · 2026
    Review
  5. Review
  6. Review
  7. Immune checkpoint molecules and spatial transcriptome profiles according to BRAF status in acral melanoma.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Incidence ofMelanoma management · 2023
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Minyu Wang *Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.ORCID 0000-0002-1051-5855
Soroor Zadeh *Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Angela PizzollaCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Kevin ThiaCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
David E GyorkiDivision of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Grant A McArthurSir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.
Richard A ScolyerThe University of Sydney, Melanoma Institute Australia, Sydney, New South Wales, Australia.ORCID 0000-0002-8991-0013
Georgina LongMelanoma Institute Australia, North Sydney, New South Wales, Australia.
James S WilmottMelanoma Institute Australia, North Sydney, New South Wales, Australia.
Miles C AndrewsDepartment of Medicine, Central Clinical School, Monash University, Clayton, Victoria, Australia.ORCID 0000-0003-1231-8641
George Au-YeungSir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.
Ali WepplerDepartment of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Shahneen SandhuSir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.
Joseph A TrapaniCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Melissa J DavisWalter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia paul.neeson@petermac.org davis.m@wehi.edu.au.
Paul Joseph NeesonCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia paul.neeson@petermac.org davis.m@wehi.edu.au.ORCID 0000-0002-2729-5887
The University of Melbourne · AUPeter MacCallum Cancer Centre · AUThe University of Sydney · AUMonash University · AURoyal North Shore Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with

methodsIn this study, we characterized the treatment-naive immune context in patients with

resultsIn single-cell data,

conclusionsIn conclusion, treatment-naive

Indexed as

MelanomaProto-Oncogene Proteins B-rafSkin NeoplasmsB-LymphocytesCD8-Positive T-LymphocytesHumansKiller Cells, NaturalMutationNatural Killer T-CellsTumor MicroenvironmentBRAF protein, humanProto-Oncogene Proteins B-rafB-lymphocytesCD4-positive T-lymphocytesCD8-positive T-lymphocytesimmunotherapymelanoma

Identifiers

PMID35383113
PMCPMC8984014
OpenAlexW4223911670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.