Evidence map›Paper›PMID 35383015›Full record

ArticleTurkish archives of pediatrics2022

A Predictor of Oxidative Stress in the Children with Measles: Thiol-Disulfide Homeostasis.

Abdullah Solmaz, Seçkin İlter, İsmail Koyuncu, Hüseyin Gümüş

Open access · diamondAbstract read
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Article in Turkish archives of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Abdullah SolmazDepartment of Pediatrics, Faculty of Medicine, Harran University, Şanlıurfa, Turkey.
Seçkin İlterDepartment of Pediatrics, Siverek State Hospital, Şanlıurfa, Turkey.
İsmail KoyuncuDepartment of Biochemistry, Faculty of Medicine, Harran University, Şanlıurfa, Turkey.
Hüseyin GümüşDepartment of Pediatrics, Faculty of Medicine, Harran University, Şanlıurfa, Turkey.
Harran University · TRSivas State Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMeasles is an infectious disease, in which oxidative stress increases. Thiols are an antioxidant substance which play a critical role in programmed cell death, detoxification, and regulation of cellular enzymatic activity, and the thiol-disulfide balance is associated with some diseases. The purpose of this study was to evaluate the thiol-disulfide balance in children with measles. MATERIALS AND

methodsThis descriptive study included case and control groups. The plasma total oxidant status level was measured using the Erel method, and the groups were compared. Before the study, informed consent was obtained from patients and Ethics Committee approval was provided (No:17/Session:05, Date: May 2019). The Pearson's and Fisher's chi-square tests were applied in the comparisons of categorical data, and independent t-test/Mann-Whitney U tests were used to compare the patient and the control groups.

resultsThere were no significant differences between the patient-control groups in terms of age and gender (P > .05). The total antioxidant status value was significantly lower, and the total oxidant status and oxidative stress index values were significantly higher (P < .05) in the patient group compared to the control group. Native thiol, total thiol, and native thiol/total thiol percentage values were significantly lower, and the disulfide, disulfide/native thiol, and disulfide/total thiol percentage values were significantly higher (P < .05) in the patients compared to the controls.

conclusionsThe detection of oxidative stress in patients with measles is important, and these results show the possibility of using the thiol/disulfide homeostasis and oxidative stress index values as biomarkers of oxidative stress in patients with measles.

Identifiers

PMID35383015
PMCPMC9366106
OpenAlexW4220975039

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.