Evidence map›Paper›PMID 35382813›Full record

ArticleRespiratory research2022

Six-minute walk distance in healthy subjects: reference standards from a general population sample.

Lucia Cazzoletti, Maria Elisabetta Zanolin, Gianluigi Dorelli, Pietro Ferrari, Luca Giuseppe Dalle Carbonare, Ernesto Crisafulli, Mulubirhan Assefa Alemayohu, Mario Olivieri, Giuseppe Verlato, Marcello Ferrari

Open access · goldAbstract read
In one paragraph

Article in Respiratory research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 74 citations in OpenAlex.

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  4. Effects of Intensive Early Physiotherapy Intervention After Myocardial Infarction on Quality of Life, Anxiety and Depression Scores: A Controlled Clinical Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Lucia Cazzoletti *Unit of Epidemiology & Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Strada Le Grazie, 8, 37134, Verona, Italy. lucia.cazzoletti@univr.it.ORCID http://orcid.org/0000-0002-1429-6282
Maria Elisabetta Zanolin *Unit of Epidemiology & Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Strada Le Grazie, 8, 37134, Verona, Italy.
Gianluigi DorelliSchool of Medicine in Sports and Exercise, Department of Medicine, University of Verona, Verona, Italy.
Pietro FerrariSchool of Medicine in Sports and Exercise, Department of Medicine, University of Verona, Verona, Italy.
Luca Giuseppe Dalle CarbonareSchool of Medicine in Sports and Exercise, Department of Medicine, University of Verona, Verona, Italy.
Ernesto CrisafulliDepartment of Medicine, Respiratory Medicine Unit, University of Verona and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.
Mulubirhan Assefa AlemayohuUnit of Epidemiology & Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Strada Le Grazie, 8, 37134, Verona, Italy.
Mario OlivieriUnit of Occupational Medicine, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
Giuseppe VerlatoUnit of Epidemiology & Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Strada Le Grazie, 8, 37134, Verona, Italy.
Marcello FerrariSchool of Medicine in Sports and Exercise, Department of Medicine, University of Verona, Verona, Italy.
University of Verona · IT

Funding

Fondazione CARIVERONA (IT) Bando 2006Ministero della Salute RF-2009-1471235
6 · The paper itself

Abstract

introductionThe 6-min walking distance (6MWD) test is a useful tool to obtain a measure of functional exercise capacity. However, reference equations have been mainly based on selected populations or small samples. The purpose of this study was to determine the reference equations to predict the 6MWD in a large Italian population sample of healthy adults of a wide age range.

methodsIn the frame of the multi case-control population-based study Gene Environment Interaction in Respiratory Diseases (GEIRD), we studied 530 healthy subjects: 287 females ranging 21-76 and 243 males ranging 21-78 years of age. We measured 6MWD, demographic and anthropometric data and collected the reported physical activity. A multiple linear regression model for the 6MWD included age, age

resultsThe mean ± SD for 6MWD was 581.4 ± 66.5 m (range 383-800 m) for females and 608.7 ± 80.1 m (range 410-875 m) for males. The reference equations were 6MWD = 8.10*age + 1.61*height

conclusionThis study is the first to describe the 6MWD in a large population sample of young, middle aged and elderly healthy Caucasian subjects, and to determine reference equations. These findings will help to improve the evaluation of Italian and European patients with diseases influencing their functional capacity.

Indexed as

Body HeightWalkingAdultAgedChildChild, PreschoolExercise TestFemaleHealthy VolunteersHumansInfantMaleMiddle AgedReference StandardsReference Values6-min walking testFunction status (activity levels)General populationHealthy subjectsReference values

Identifiers

PMID35382813
PMCPMC8985335
OpenAlexW4223435878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.