ArticleThe journal of headache and pain2022
Abnormalities in resting-state EEG microstates are a vulnerability marker of migraine.
Article in The journal of headache and pain, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Resting-state electroencephalography and magnetoencephalography in migraine-a systematic review and meta-analysis.The journal of headache and pain · 2024Pooled it
- Headache-related circuits and high frequencies evaluated by EEG, MRI, PET as potential biomarkers to differentiate chronic and episodic migraine: Evidence from a systematic review.The journal of headache and pain · 2022Pooled it
- Analgesic effects of high-frequency rTMS on pain anticipation and perception.Communications biology · 2024Trial
- Salience Network Dynamics Across Spontaneous Attacks, Interictal Rest and Interictal Pain Imagery in Menstrually Related Migraine.Brain topography · 2026Article
- High serum uric acid levels explains the negative impact of the altitude adaptation index on the brain electroencephalographic Microstate D under high-altitude hypoxic conditions.Frontiers in integrative neuroscience · 2026Article
- EEG microstate and functional connectivity analyses for differentiating suicide attempt from suicidal ideation in major depressive disorder.Journal of psychiatry & neuroscience : JPN · 2025Article
- Altered intra- and inter-network functional connectivity in pituitary adenomas with chiasmal compression.Quantitative imaging in medicine and surgery · 2025Article
- Differential resting-state MEG microstate patterns in migraineurs: a cross-sectional study.The journal of headache and pain · 2025Article
- Neural oscillation mechanisms of repetitive subconcussive impacts: a network study of microstate-specific cross-frequency coupling.The journal of headache and pain · 2025Article
- A novel ST-GCN model based on homologous microstate for subject-independent seizure prediction.Scientific reports · 2025Article
- Preemptive transcranial direct current stimulation mitigates susceptibility to persistent pain.Communications biology · 2025Article
- Pathophysiological changes in incentive processing in episodic migraine: a preliminary event-related potential study.Social cognitive and affective neuroscience · 2025Article
- Electroencephalographic Resting-State Microstates are Unstable in Visual Snow Syndrome.Brain and behavior · 2025Article
- Altered microstate C and D dynamics in high social anxiety: a resting-state EEG study.Frontiers in psychology · 2025Article
- Analysis of the microstates of prolonged disorders of consciousness.Frontiers in neurology · 2025Article
- A novel approach for migraine detection using localized component filtering and electroencephalographic spectral asymmetry index.Current journal of neurology · 2024Article
- Electroencephalography microstate alterations reflect potential double-edged cognitive adaptation in Ménière's disease.CNS neuroscience & therapeutics · 2024Article
- EEG Changes in Migraine-Can EEG Help to Monitor Attack Susceptibility?Brain sciences · 2024Review
- A pilot study on a patient with refractory headache: Personalized deep brain stimulation through stereoelectroencephalography.iScience · 2024Article
- Resting-state electroencephalography microstates as a marker of photosensitivity in juvenile myoclonic epilepsy.Brain communications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundResting-state EEG microstates are thought to reflect brief activations of several interacting components of resting-state brain networks. Surprisingly, we still know little about the role of these microstates in migraine. In the present study, we attempted to address this issue by examining EEG microstates in patients with migraine without aura (MwoA) during the interictal period and comparing them with those of a group of healthy controls (HC).
methodsResting-state EEG was recorded in 61 MwoA patients (50 females) and 66 HC (50 females). Microstate parameters were compared between the two groups. We computed four widely identified canonical microstate classes A-D.
resultsMicrostate classes B and D displayed higher time coverage and occurrence in the MwoA patient group than in the HC group, while microstate class C exhibited significantly lower time coverage and occurrence in the MwoA patient group. Meanwhile, the mean duration of microstate class C was significantly shorter in the MwoA patient group than in the HC group. Moreover, among the MwoA patient group, the duration of microstate class C correlated negatively with clinical measures of headache-related disability as assessed by the six-item Headache Impact Test (HIT-6). Finally, microstate syntax analysis showed significant differences in transition probabilities between the two groups, primarily involving microstate classes B, C, and D.
conclusionsBy exploring EEG microstate characteristics at baseline we were able to explore the neurobiological mechanisms underlying altered cortical excitability and aberrant sensory, affective, and cognitive processing, thus deepening our understanding of migraine pathophysiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.