Evidence map›Paper›PMID 35382559›Full record

ArticleEpigenomics2022

Distinct cytosine modification profiles define epithelial-to-mesenchymal cell-state transitions.

Min Kyung Lee, Meredith S Brown, Owen M Wilkins, Diwakar R Pattabiraman, Brock C Christensen

Open access · greenAbstract read
In one paragraph

Article in Epigenomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Min Kyung LeeDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.ORCID 0000-0001-9558-4819
Meredith S BrownDepartment of Molecular & Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.
Owen M WilkinsNorris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.ORCID 0000-0002-0882-9484
Diwakar R PattabiramanDepartment of Molecular & Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.ORCID 0000-0002-2418-6458
Brock C ChristensenDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.ORCID 0000-0003-3022-426X
Dartmouth College · USDartmouth–Hitchcock Medical Center · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Zhao - Proj 2P20GM130454 · NIGMS · DARTMOUTH COLLEGE · PI MICHAEL L WHITFIELD · 2019 to 2026
$27.2M
DNA-based Immune Phenotyping in HNSCC for Biomarkers of Response to ImmunotherapyR01CA253976 · NCI · BROWN UNIVERSITY · PI CHRISTENSEN, BROCK C, KELSEY, KARL TIMOTHY · 2021 to 2025
$3.3M
Uncovering the basis and implications of lineage plasticity in breast cancerR01CA267691 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Todd W. Miller · 2022 to 2026
$1.8M
Exploiting the epithelial-to-mesenchymal transition for the differentiation of cancer stem cellsR00CA201574 · NCI · DARTMOUTH COLLEGE · PI PATTABIRAMAN, DIWAKAR R · 2018 to 2020
$686k
NCI NIH HHS P30 CA023108NCI NIH HHS R00 CA201574NCI NIH HHS R01 CA253976NCI NIH HHS R01 CA267691NIGMS NIH HHS P20 GM130454
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CytosineDNA MethylationChromatinEpigenesis, GeneticEpithelial-Mesenchymal TransitionHumansTranscription FactorsChromatinCytosineTranscription Factorscytosine modificationsDNA methylationepithelial-to-mesenchymal transitionhydroxymethylationmulti-omic epigenomes

Identifiers

PMID35382559
PMCPMC9118069
OpenAlexW4226050531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.