Evidence map›Paper›PMID 35382463›Full record

ArticleChemical science2022

Near-infrared fluorescent probe for hydrogen sulfide: high-fidelity ferroptosis evaluation

Tianyu Liang, Taotao Qiang, Longfang Ren, Fei Cheng, Baoshuai Wang, Mingli Li, Wei Hu, Tony D James

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Fluorescent small molecule donors.Chemical Society reviews · 2024
    Review
  8. Review
  9. An Expanded Palette of Fluorescent COS/HAngewandte Chemie (International ed. in English) · 2024
    Article
  10. Review
  11. A multi-functional fluorescent probe for visualization of HAnalytical and bioanalytical chemistry · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Visualization of ferroptosis in brain diseases and ferroptosis-inducing nanomedicine for glioma.American journal of nuclear medicine and molecular imaging · 2023
    Review
  17. HFrontiers in chemistry · 2023
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Tianyu LiangCollege of Bioresources and Materials Engineering, Shaanxi Collaborative Innovation Center of Industrial Auxiliary Chemistry & Technology, Shaanxi University of Science & Technology Xi'an 710021 China qiangtt515@163.com huwchem@163.com.
Taotao QiangCollege of Bioresources and Materials Engineering, Shaanxi Collaborative Innovation Center of Industrial Auxiliary Chemistry & Technology, Shaanxi University of Science & Technology Xi'an 710021 China qiangtt515@163.com huwchem@163.com.ORCID https://orcid.org/0000-0003-3505-2049
Longfang RenCollege of Bioresources and Materials Engineering, Shaanxi Collaborative Innovation Center of Industrial Auxiliary Chemistry & Technology, Shaanxi University of Science & Technology Xi'an 710021 China qiangtt515@163.com huwchem@163.com.
Fei ChengCollege of Bioresources and Materials Engineering, Shaanxi Collaborative Innovation Center of Industrial Auxiliary Chemistry & Technology, Shaanxi University of Science & Technology Xi'an 710021 China qiangtt515@163.com huwchem@163.com.
Baoshuai WangCollege of Bioresources and Materials Engineering, Shaanxi Collaborative Innovation Center of Industrial Auxiliary Chemistry & Technology, Shaanxi University of Science & Technology Xi'an 710021 China qiangtt515@163.com huwchem@163.com.
Mingli LiCollege of Bioresources and Materials Engineering, Shaanxi Collaborative Innovation Center of Industrial Auxiliary Chemistry & Technology, Shaanxi University of Science & Technology Xi'an 710021 China qiangtt515@163.com huwchem@163.com.
Wei HuCollege of Bioresources and Materials Engineering, Shaanxi Collaborative Innovation Center of Industrial Auxiliary Chemistry & Technology, Shaanxi University of Science & Technology Xi'an 710021 China qiangtt515@163.com huwchem@163.com.ORCID https://orcid.org/0000-0001-9639-0338
Tony D JamesDepartment of Chemistry, University of Bath Bath BA27AY UK t.d.james@bath.ac.uk.ORCID https://orcid.org/0000-0002-4095-2191
Shaanxi University of Science and Technology · CNUniversity of Bath · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is closely associated with cancer, neurodegenerative diseases and ischemia-reperfusion injury and the detection of its pathological process is very important for early disease diagnosis. Fluorescence based sensing technologies have become excellent tools due to the real-time detection of cellular physiological or pathological processes. However, to date the detection of ferroptosis using reducing substances as markers has not been achieved since the reducing substances are not only present at extremely low concentrations during ferroptosis but also play a key role in the further development of ferroptosis. Significantly, sensors for reducing substances usually consume reducing substances, instigating a redox imbalance, which further aggravates the progression of ferroptosis. In this work, a H

Identifiers

PMID35382463
PMCPMC8905919
OpenAlexW4213195586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.