Evidence map›Paper›PMID 35382443›Full record

ReviewAPL bioengineering2022

The yellow brick road to nuclear membrane mechanotransduction.

Zhouyang Shen, Miklós Lengyel, Philipp Niethammer

Abstract readReview
In one paragraph

Review in APL bioengineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Mechanobiology of the cell nucleus.APL bioengineering · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Miklós LengyelCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.ORCID https://orcid.org/0000-0001-6382-6369
Philipp NiethammerCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.ORCID https://orcid.org/0000-0003-4175-4012

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Chemical and Physical Mechanisms of Wound DetectionR35GM140883 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Philipp Michael Niethammer · 2021 to 2026
$3.8M
Biomechanical control of inflammation by the nuclear membraneR01GM127356 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI NIETHAMMER, PHILIPP MICHAEL · 2018 to 2021
$1.6M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R01 GM127356NIGMS NIH HHS R35 GM140883
6 · The paper itself

Abstract

The nuclear membrane may function as a mechanosensory surface alongside the plasma membrane. In this Review, we discuss how this idea emerged, where it currently stands, and point out possible implications, without any claim of comprehensiveness.

Identifiers

PMID35382443
PMCPMC8967412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.