ArticleACS omega2022
An Efficient and Versatile Deep Eutectic Solvent-Mediated Green Method for the Synthesis of Functionalized Coumarins.
Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Recent Advances in the Gewald Reaction: A Valuable Tool for the Synthesis of Thiophene Derivatives.Topics in current chemistry (Cham) · 2026Review
- Organic Named Reactions in Green Deep Eutectic Solvents (DESs).Topics in current chemistry (Cham) · 2025Review
- A novel acidic deep eutectic solvent for sustainable and efficient coumarin synthesis.Scientific reports · 2025Article
- Natural deep eutectic solvent-based pectin-chitosan composite hydrogel films: A novel pH-responsive color indicator for food packaging systems.Current research in food science · 2025Article
- Syntheses, reactivity, and biological applications of coumarins.Frontiers in chemistry · 2024Review
- Cesium salt of tungstophosphoric acid/mesoporous (zirconia-silica) composite for highly efficient synthesis of 7-hydroxy-4-methyl coumarin and removal of methylene blue.RSC advances · 2023Article
- Review
- An ultrasound assisted, ionic liquid-molecular iodine synergy driven efficient green synthesis of pyrrolobenzodiazepine-triazole hybrids as potential anticancer agents.Frontiers in pharmacology · 2023Article
- Dithieno[3,2-RSC advances · 2022Review
- Article
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Authors and funding
2 authors.
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Abstract
Herein, we report a green and efficient synthetic route for the construction of diverse functionalized coumarins in good-to-excellent yields (60-98%) via the Pechmann condensation. The optimized synthetic route involves a biodegradable, reusable, and inexpensive deep eutectic solvent (DES) of choline chloride and l-(+)-tartaric acid in a ratio of 1:2 at 110 °C. Interestingly, phloroglucinol and ethyl acetoacetate, upon reaction, furnished the functionalized coumarin (
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Registered trials
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