Evidence map›Paper›PMID 35382230›Full record

ArticleInformatics in medicine unlocked2022

Statistical analysis of COVID-19 infection severity in lung lobes from chest CT.

Mehdi Yousefzadeh, Mozhdeh Zolghadri, Masoud Hasanpour, Fatemeh Salimi, Ramezan Jafari, Mehran Vaziri Bozorg, Sara Haseli, Abolfazl Mahmoudi Aqeel Abadi, Shahrokh Naseri, Mohammadreza Ay and 1 more

Open access · goldAbstract read
In one paragraph

Article in Informatics in medicine unlocked, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Mehdi YousefzadehDepartment of Physics, Shahid Beheshti University, Tehran, Iran.
Mozhdeh ZolghadriDepartment of Medical Physics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Masoud HasanpourResearch Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran.
Fatemeh SalimiMedical Physics and Biomedical Engineering Department, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Ramezan JafariDepartment of Radiology and Health Research Center Baqiyatallah University of Medical Sciences, Tehran, Iran.
Mehran Vaziri BozorgDepartment of Radiology, Kasra Hospital, Tehran, Iran.
Sara HaseliChronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
Abolfazl Mahmoudi Aqeel AbadiMedical Physics and Biomedical Engineering Department, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Shahrokh NaseriDepartment of Physics, Shahid Beheshti University, Tehran, Iran.
Mohammadreza AyResearch Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad-Reza Nazem-ZadehResearch Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRMashhad University of Medical Sciences · IRBaqiyatallah University of Medical Sciences · IRInstitute for Research in Fundamental Sciences · IRMasih Daneshvari Hospital · IRSina Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detection of the COVID 19 virus is possible through the reverse transcription-polymerase chain reaction (RT-PCR) kits and computed tomography (CT) images of the lungs. Diagnosis via CT images provides a faster diagnosis than the RT-PCR method does. In addition to low false-negative rate, CT is also used for prognosis in determining the severity of the disease and the proposed treatment method. In this study, we estimated a probability density function (PDF) to examine the infections caused by the virus. We collected 232 chest CT of suspected patients and had them labeled by two radiologists in 6 classes, including a healthy class and 5 classes of different infection severity. To segment the lung lobes, we used a pre-trained U-Net model with an average Dice similarity coefficient (DSC) greater than 0.96. First, we extracted the PDF to grade the infection of each lobe and selected five specific thresholds as feature vectors. We then assigned this feature vector to a support vector machine (SVM) model and made the final prediction of the infection severity. Using the T-Test statistics, we calculated the

Indexed as

COVID-19CT scanLung lobes segmentationProbability density functionStatistical analysisSupport vector machine

Identifiers

PMID35382230
PMCPMC8970623
OpenAlexW4220775982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.