Evidence map›Paper›PMID 35381904›Full record

Trial reportClinical research in cardiology : official journal of the German Cardiac Society2022

The effects of positive end-expiratory pressure on cardiac function: a comparative echocardiography-conductance catheter study.

David Berger, Olivier Wigger, Stefano de Marchi, Martin R Grübler, Andreas Bloch, Reto Kurmann, Odile Stalder, Kaspar Felix Bachmann, Stefan Bloechlinger

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical research in cardiology : official journal of the German Cardiac Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02267291 (Impact of Non-invasive Positive Pressure Ventilation on Cardiac Function and Echocardiographic Parameters), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02267291 nacompletednot on this map

Impact of Non-invasive Positive Pressure Ventilation on Cardiac Function and Echocardiographic Parameters

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2015 to 2018Enrolled30ConditionsHeart Function Tests, Hemodynamics, Noninvasive Ventilation, Circulatory and Respiratory Physiological PhenomenaArmsNon-invasive positive pressure ventilation
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

David Berger *Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland. David.berger@insel.ch.ORCID http://orcid.org/0000-0003-0705-6341
Olivier Wigger *Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Stefano de MarchiDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Martin R GrüblerDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Andreas BlochDepartment of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland.
Reto KurmannDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Odile StalderCTU Bern, University of Bern, Bern, Switzerland.
Kaspar Felix BachmannDepartment of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland.
Stefan BloechlingerDepartment of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland.
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEchocardiographic parameters of diastolic function depend on cardiac loading conditions, which are altered by positive pressure ventilation. The direct effects of positive end-expiratory pressure (PEEP) on cardiac diastolic function are unknown.

methodsTwenty-five patients without apparent diastolic dysfunction undergoing coronary angiography were ventilated noninvasively at PEEPs of 0, 5, and 10 cmH

resultsτ values for intracavitary cardiac pressure increased with the PEEP (n = 25; no PEEP, 44 ± 5 ms; 5 cmH

conclusionsPEEP does not affect active diastolic relaxation or passive ventricular filling properties. Dynamic echocardiographic filling parameters may reflect changing loading conditions rather than intrinsic diastolic function. PEEP may have slight positive inotropic effects. CLINICAL

trial registrationhttps://clinicaltrials.gov/ct2/show/NCT02267291 , registered 17. October 2014.

Indexed as

Heart VentriclesPositive-Pressure RespirationCathetersDiastoleEchocardiographyHumansDiastolic functionEchocardiographyEnd-diastolic pressureEnd-systolic pressureMechanical ventilationPositive end-expiratory pressureVolume relationship

Identifiers

PMID35381904
PMCPMC9151717
OpenAlexW4226243053

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.