Evidence map›Paper›PMID 35381691›Full record

SynthesisAsian journal of andrology

Predictors of microsurgical varicocelectomy efficacy in male infertility treatment: critical assessment and systematization.

Azizbek B Shomarufov, Vladimir A Bozhedomov, Nikolay I Sorokin, Igor P Matyukhov, Abdukodir A Fozilov, Shukhrat A Abbosov, Armais A Kamalov

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Azizbek B ShomarufovDepartment of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow 119991, Russia.
Vladimir A BozhedomovDepartment of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow 119991, Russia.
Nikolay I SorokinDepartment of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow 119991, Russia.
Igor P MatyukhovDepartment of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow 119991, Russia.
Abdukodir A FozilovRepublican Specialized Scientific-Practical Medical Center of Urology, Tashkent 100109, Uzbekistan.
Shukhrat A AbbosovDepartment of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow 119991, Russia.
Armais A KamalovDepartment of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow 119991, Russia.
Lomonosov Moscow State University · RUTashkent Medical Academy · UZTashkent Pediatric Medical Institute · UZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review, we tried to systematize all the evidence (from PubMed [MEDLINE], Scopus, Cochrane Library, EBSCO, Embase, and Google Scholar) from 1993 to 2021 on the predictors of microsurgical varicocelectomy efficacy in male infertility treatment. Regarding the outcomes of varicocele repair, we considered semen improvement and pregnancy and analyzed them separately. Based on the 2011 Oxford CEBM Levels of Evidence, we assigned a score to each trial that studied the role of the predictor. We systematized the studied predictors based on the total points, which were, in turn, calculated based on the number and quality of studies that confirmed or rejected the studied predictor as significant, into three levels of significance: predictors of high, moderate, and low clinical significance. Preoperative total motile sperm count (TMSC) coupled with sperm concentration can be a significant predictor of semen improvement and pregnancy after varicocelectomy. In addition, for semen improvement alone, scrotal Doppler ultrasound (DUS) parameters, sperm DNA fragmentation index (DFI), and bilateral varicocelectomy are reliable predictors of microsurgical varicocelectomy efficacy.

Indexed as

Infertility, MaleVaricoceleFemaleHumansMaleMicrosurgeryPregnancySemenSperm CountSperm Motilitymale infertilitymicrosurgical varicocelectomypredictorpregnancysemenvaricocele

Identifiers

PMID35381691
PMCPMC9933953
OpenAlexW4226065710

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.