Evidence map›Paper›PMID 35381617›Full record

ArticleMethods of information in medicine2022

A Methodological Approach to Validate Pneumonia Encounters from Radiology Reports Using Natural Language Processing.

AlokSagar Panny, Harshad Hegde, Ingrid Glurich, Frank A Scannapieco, Jayanth G Vedre, Jeffrey J VanWormer, Jeffrey Miecznikowski, Amit Acharya

Open access · greenAbstract read
In one paragraph

Article in Methods of information in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

AlokSagar PannyCenter for Oral-Systemic Health, Marshfield Clinic Research Institute, Marshfield, Wisconsin, United States.
Harshad HegdeCenter for Oral-Systemic Health, Marshfield Clinic Research Institute, Marshfield, Wisconsin, United States.
Ingrid GlurichCenter for Oral-Systemic Health, Marshfield Clinic Research Institute, Marshfield, Wisconsin, United States.
Frank A ScannapiecoDepartment of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, New York, United States.
Jayanth G VedreDepartment of Critical Care Medicine, Marshfield Clinic Health System, Marshfield, Wisconsin, United States.
Jeffrey J VanWormerCenter for Clinical Epidemiology and Population Health, Marshfield Clinic Research Institute, Marshfield, Wisconsin, United States.
Jeffrey MiecznikowskiDepartment of Biostatistics, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, New York, United States.
Amit AcharyaCenter for Oral-Systemic Health, Marshfield Clinic Research Institute, Marshfield, Wisconsin, United States.
Marshfield Clinic · USUniversity at Buffalo, State University of New York · USMarshfield Clinic · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Secondary Analysis of EHR Data to Examine Relative Impact of Oral Health History on Incident Pneumonia by SettingsR03DE027020 · NIDCR · MARSHFIELD CLINIC RESEARCH FOUNDATION · PI ACHARYA, AMIT · 2018 to 2019
$335k
NCATS NIH HHS UL1 TR001412NIDCR NIH HHS R03 DE027020
6 · The paper itself

Abstract

introductionPneumonia is caused by microbes that establish an infectious process in the lungs. The gold standard for pneumonia diagnosis is radiologist-documented pneumonia-related features in radiology notes that are captured in electronic health records in an unstructured format.

objectiveThe study objective was to develop a methodological approach for assessing validity of a pneumonia diagnosis based on identifying presence or absence of key radiographic features in radiology reports with subsequent rendering of diagnostic decisions into a structured format.

methodsA pneumonia-specific natural language processing (NLP) pipeline was strategically developed applying Clinical Text Analysis and Knowledge Extraction System (cTAKES) to validate pneumonia diagnoses following development of a pneumonia feature-specific lexicon. Radiographic reports of study-eligible subjects identified by International Classification of Diseases (ICD) codes were parsed through the NLP pipeline. Classification rules were developed to assign each pneumonia episode into one of three categories: "positive," "negative," or "not classified: requires manual review" based on tagged concepts that support or refute diagnostic codes.

resultsA total of 91,998 pneumonia episodes diagnosed in 65,904 patients were retrieved retrospectively. Approximately 89% (81,707/91,998) of the total pneumonia episodes were documented by 225,893 chest X-ray reports. NLP classified and validated 33% (26,800/81,707) of pneumonia episodes classified as "Pneumonia-positive," 19% as (15401/81,707) as "Pneumonia-negative," and 48% (39,209/81,707) as "episode classification pending further manual review." NLP pipeline performance metrics included accuracy (76.3%), sensitivity (88%), and specificity (75%).

conclusionThe pneumonia-specific NLP pipeline exhibited good performance comparable to other pneumonia-specific NLP systems developed to date.

Indexed as

PneumoniaRadiologyElectronic Health RecordsHumansNatural Language ProcessingRetrospective Studies

Identifiers

PMID35381617
PMCPMC9391313
OpenAlexW4225114766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.