Evidence map›Paper›PMID 35381471›Full record

ArticlePregnancy hypertension2022

Perinatal outcomes and 2017 ACC/AHA blood pressure categories.

Martha A Tesfalul, Jeffrey D Sperling, Cinthia Blat, Nisha I Parikh, Juan M Gonzalez-Velez, Marya G Zlatnik, Mary E Norton

Abstract read
In one paragraph

Article in Pregnancy hypertension, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Martha A TesfalulUniversity of California, San Francisco, Department of Obstetrics, Gynecology, & Reproductive Sciences, Division of Maternal-Fetal Medicine, 490 Illinois Street, 10th Floor, Box 0132, San Francisco, CA 94143, USA. Electronic address: martha.tesfalul@ucsf.edu.
Jeffrey D SperlingKaiser Permanente, Modesto, Department of Obstetrics & Gynecology, 4601 Dale Road, Modesto, CA 95356, USA.
Cinthia BlatUniversity of California, San Francisco, Department of Obstetrics, Gynecology, & Reproductive Sciences, Division of Maternal-Fetal Medicine, 490 Illinois Street, 10th Floor, Box 0132, San Francisco, CA 94143, USA.
Nisha I ParikhUniversity of California, San Francisco, Department of Medicine, Division of Cardiology, 535 Mission Bay Boulevard South, San Francisco, CA 94158, USA.
Juan M Gonzalez-VelezUniversity of California, San Francisco, Department of Obstetrics, Gynecology, & Reproductive Sciences, Division of Maternal-Fetal Medicine, 490 Illinois Street, 10th Floor, Box 0132, San Francisco, CA 94143, USA.
Marya G ZlatnikUniversity of California, San Francisco, Department of Obstetrics, Gynecology, & Reproductive Sciences, Division of Maternal-Fetal Medicine, 490 Illinois Street, 10th Floor, Box 0132, San Francisco, CA 94143, USA.
Mary E NortonUniversity of California, San Francisco, Department of Obstetrics, Gynecology, & Reproductive Sciences, Division of Maternal-Fetal Medicine, 490 Illinois Street, 10th Floor, Box 0132, San Francisco, CA 94143, USA.

Funding

Transdisciplinary Research Training to Reduce Disparities in Preterm Birth and Improve Maternal and Neonatal OutcomesT32HD098057 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KUPPERMANN, MIRIAM · 2019 to 2023
$1.4M
NICHD NIH HHS T32 HD098057
6 · The paper itself

Abstract

objectiveTo evaluate the association of blood pressure category < 20 weeks according to the 2017 American College of Cardiology/American Heart Association (ACC/AHA) criteria with adverse perinatal outcomes. STUDY

designA retrospective cohort study of singleton deliveries between 1/2014 and 10/2017 was undertaken. Blood pressure category assigned by 2017 ACC/AHA criteria applied to blood pressures prior to 20 weeks gestation: normal (systolic < 120 and diastolic < 80), elevated blood pressure (systolic 120-129 and diastolic < 80 mmHg), stage 1 hypertension (systolic 130-139 and/or diastolic 80-89), stage 2 hypertension (prior diagnosis of chronic hypertension or systolic ≥ 140 or diastolic ≥ 90 mmHg).

main outcome measuresThe primary outcome was preeclampsia. Secondary outcomes included preterm birth and postpartum readmission. Chi-square, ANOVA and Kruskal-Wallis tests and multivariable Poisson regression were used for analysis.

resultsOf the 6,067 eligible pregnancies, 3,855 (63.5%) had normotensive blood pressure, 1,224 (20.2%) elevated blood pressure, 624 (10.3%) stage 1 hypertension, and 364 (6.0%) stage 2 hypertension. Compared to 4.6% prevalence of preeclampsia among normotensive pregnancies, higher categories were associated with higher preeclampsia prevalence: elevated blood pressure (10.7%, adjusted relative risk (aRR) 2.2, 95% confidence interval (CI) 1.8-2.6), stage 1 hypertension (15.1%, aRR 2.7, 95% CI 2.2-3.4) and stage 2 hypertension (38.7%, aRR 6.2, 95% CI 5.1-7.4). Non-normal categories were also associated with a higher risk of preterm birth and postpartum readmission.

conclusionPatients with elevated blood pressure and stage 1 and 2 hypertension at < 20 weeks are at increased risk of adverse obstetric perinatal outcomes.

Indexed as

HypertensionPre-EclampsiaPremature BirthBlood PressureFemaleHumansInfant, NewbornPregnancyRetrospective StudiesUnited StatesBlood pressureHypertensionPostpartum readmissionPreeclampsiaPregnancyPreterm birth

Identifiers

PMID35381471
PMCPMC12009628

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.