Evidence map›Paper›PMID 35381337›Full record

ArticleMethods (San Diego, Calif.)2022

Near-infrared fluorescent probe based on rhodamine derivative for detection of NADH in live cells.

Yibin Zhang, Dilka Liyana Arachchige, Adenike Olowolagba, Rudy L Luck, Haiying Liu

Abstract read
In one paragraph

Article in Methods (San Diego, Calif.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  9. Dynamic insights into mitochondrial function: Monitoring viscosity and SOJournal of photochemistry and photobiology. B, Biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yibin ZhangDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. Electronic address: yibinz@mtu.edu.
Dilka Liyana ArachchigeDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA.
Adenike OlowolagbaDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA.
Rudy L LuckDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. Electronic address: rluck@mtu.edu.
Haiying LiuDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. Electronic address: hyliu@mtu.edu.

Funding

Ratiometric Near-infrared Fluorescent Probes for Lysosomal pH in Living CellsR15GM114751 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI LIU, HAIYING · 2015 to 2019
$798k
Near-infrared Fluorescent Probes for Sensitive Detection of NADH in Live CellsR15GM146206 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI LIU, HAIYING · 2022 to 2024
$588k
NIGMS NIH HHS R15 GM114751NIGMS NIH HHS R15 GM146206
6 · The paper itself

Abstract

A near-infrared fluorescent probe was prepared for selective detection of reduced nicotinamide adenine dinucleotide (NADH) in live cells. The probe turns off the fluorescence with a closed spironolactone switch. However, reduction of the probe by NADH turns on fluorescence at 740 nm. Theoretical calculations suggest a more planar arrangement between the rhodamine and quinoline moieties with increased π-delocalization resulting from reduction.

Indexed as

Fluorescent DyesNADFluorescenceHeLa CellsHumansRhodaminesFluorescent DyesNADRhodaminesCellular ImagingComputation chemistryNADHNear-infrared fluorescent probe

Identifiers

PMID35381337
PMCPMC9233151

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.