ArticlePloS one2022
Treatment outcomes of diabetic ketoacidosis among diabetes patients in Ethiopia. Hospital-based study.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Prevalence of in-hospital mortality among adult patients with diabetic ketoacidosis in Ethiopia: a systematic review and meta-analysis of observational studies.Frontiers in clinical diabetes and healthcare · 2025Pooled it
- Clinical Predictors of Time to Hospital Discharge in Children With New-Onset Diabetic Ketoacidosis in Zambia: A Retrospective Cohort Study.Endocrinology, diabetes & metabolism · 2026Article
- Time to resolution of diabetic ketoacidosis in children with type 1 diabetes: a survival analysis of clinical predictors.BMC endocrine disorders · 2026Article
- Time to Resolution of Diabetic Ketoacidosis and Its Predictors among Adult Diabetic Patients in Public Hospitals of Northeast, Ethiopia.Scientific reports · 2026Article
- Clinical profile of diabetic ketoacidosis and its severity in adults: evidence from ALERT Comprehensive Specialized Hospital.BMC endocrine disorders · 2026Article
- Prevalence of treatment outcomes and associated factors of diabetic ketoacidosis among adult diabetic patients admitted to Debre Markos comprehensive specialized hospital, northwest Ethiopia.European journal of medical research · 2025Article
- Comments on "association between triglyceride-glucose index upon admission and the subsequent occurrence of acute kidney injury in adult patients with diabetic ketoacidosis: a single-center retrospective cohort study".Annals of medicine · 2025Article
- Recurrence and predictors of diabetic ketoacidosis among individuals with diabetes mellitus in public hospitals of Bahir Dar city, Ethiopia.Scientific reports · 2025Article
- Determinants of diabetic ketoacidosis among adults with diabetes mellitus at the Ambo town Hospitals, Ethiopia.Scientific reports · 2025Article
- Risk factors of diabetic ketoacidosis among patients with diabetes attending at public hospitals of East Gojjam Zone, Northwest Ethiopia: an unmatched case - control study.BMC endocrine disorders · 2025Article
- Outcomes following hospitalization for diabetic ketoacidosis in patients with cardiovascular disease.Endocrine connections · 2025Article
- Diabetic ketoacidosis treatment outcomes and associated factors among adult diabetic patients in Ethiopia: A systematic review and meta-analysis.Metabolism open · 2025Article
- Article
- Clinical presentation and outcomes of care in adults with diabetic ketoacidosis pre-COVID-19 and during-COVID-19 at a tertiary, referral hospital in Nairobi, Kenya.BMC endocrine disorders · 2024Article
- Poor treatment outcome and associated factors of hyperglycemic emergencies among diabetic patients in Ethiopia: A systematic review and meta-analysis.Metabolism open · 2024Article
- Incidence and predictors of hyperglycemic emergencies among adult diabetic patients at public hospitals of Sidama Region and Gedeo Zone, Southern Ethiopia: a survival analysis.Therapeutic advances in endocrinology and metabolism · 2024Article
- Diabetic ketoacidosis treatment outcomes and its associated factors among adult patients with diabetes mellitus admitted to public hospitals in Nekemte Town, Ethiopia: a cross-sectional study.Frontiers in clinical diabetes and healthcare · 2024Article
- Outcome of Diabetic Keto Acidosis Treatment and Associated Factors Among Adult Patients Admitted to Emergency and Medical Wards at St. Paul's Hospital, Addis Ababa Ethiopia, 2023: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Development and Validation of a Risk Prediction Model for Ketosis-Prone Type 2 Diabetes Mellitus Among Patients Newly Diagnosed with Type 2 Diabetes Mellitus in China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- An Audit of Factors Impacting the Time to Resolution of the Metabolic Parameters in Diabetic Ketoacidosis Patients.Cureus · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThere was limited data on treatment outcomes among patients with diabetic ketoacidosis (DKA) in Ethiopia.
objectiveThe aim of the study was to determine the treatment outcomes of DKA patients attending Debre Tabor General Hospital.
methodA retrospective study was conducted at Debre Tabor General Hospital and data were collected from June 1 to June 30 of 2018. Participants included in the study were all diabetic patients with DKA admitted from August 2010 to May 31, 2018. The primary outcomes were the treatment outcomes of DKA including (in-hospital glycemic control, the length of hospital stay and in-hospital mortality). The statistical analysis was carried out using Statistical Package for Social Sciences (SPSS) version 22. Descriptive statistics was presented in the form of means with standard deviation and binary regression was conducted to determine factors that affect length of hospital stay among DKA patients.
result387 patients were included in the study. The mean age of patients was 33.30± 14.96 years. The most common precipitating factor of DKA was new onset diabetes mellitus 150(38.8%). The mean length of hospital stay was 4.64(±2.802) days. The mean plasma glucose at admission and discharge was 443.63(±103.33) and 172.94 (±80.60) mg/dL, respectively. The majority 370 (95.60%) of patients improved and discharged whereas 17 (4.40%) patients died in the hospital. Patients with mild and moderate DKA showed short hospital stay; AOR: 0.16 [0.03-0.78] and AOR:0.17[0.03-0.96] compared with severe DKA. Diabetic ketoacidosis precipitated by infection were nearly five times more likely to have long hospital stay than DKA precipitated by other causes; AOR: 4.59 [1.08-19.42]. In addition, serum glucose fluctuation during hospitalization increased the likelihood of long hospital stay, AOR: 2.15[1.76-2.63].
conclusionsNew onset type 1 diabetes was the major precipitating factor for DKA. Admitted DKA patients remained in hospital for a duration of approximately five days. About five out of hundred DKA patients ended up with death in the hospital. Infection, serum glucose fluctuations and severity of DKA were determinants of long hospital stay. Early prevention of precipitating factors and adequate management of DAK are warranted to reduce length of hospital stay and mortality.
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