Evidence map›Paper›PMID 35380814›Full record

ArticleJournal of the American Chemical Society2022

Reverse Electron Transfer by Respiratory Complex I Catalyzed in a Modular Proteoliposome System.

John J Wright, Olivier Biner, Injae Chung, Nils Burger, Hannah R Bridges, Judy Hirst

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Functional Reconstitution of Mitochondrial Respiratory Supercomplexes.Journal of visualized experiments : JoVE · 2026
    Article
  3. Review
  4. Improving cell-free metabolism through direct integration of artificial respiratory chains.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Global conformations ofScience advances · 2025
    Article
  9. Action at a distance: The remarkable coupling of COProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. Respiratory complex IIIbioRxiv : the preprint server for biology · 2025
    Article
  13. A splendid molecular factory: De- and reconstruction of the mammalian respiratory chain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

John J WrightMedical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, U.K.ORCID 0000-0001-8987-4449
Olivier BinerMedical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, U.K.ORCID 0000-0001-6935-2475
Injae ChungMedical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, U.K.ORCID 0000-0002-2902-4677
Nils BurgerMedical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, U.K.ORCID 0000-0003-3227-8894
Hannah R BridgesMedical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, U.K.ORCID 0000-0001-6890-6050
Judy HirstMedical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, U.K.ORCID 0000-0001-8667-6797
MRC Mitochondrial Biology Unit · GB

Funding

Medical Research Council MC_UU_00015/2Medical Research Council MC_ UU_00015/7Medical Research Council MC_UU_00015/7Medical Research Council MC_UU_00028/1
6 · The paper itself

Abstract

Respiratory complex I is an essential metabolic enzyme that uses the energy from NADH oxidation and ubiquinone reduction to translocate protons across an energy transducing membrane and generate the proton motive force for ATP synthesis. Under specific conditions, complex I can also catalyze the reverse reaction, Δp-linked oxidation of ubiquinol to reduce NAD

Indexed as

ElectronsElectron Transport Complex IAnimalsCatalysisElectron TransportMammalsNADOxidation-ReductionElectron Transport Complex INAD

Identifiers

PMID35380814
PMCPMC9026280
OpenAlexW4223501757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.