Trial reportAmerican journal of physiology. Regulatory, integrative and comparative physiology2022
Influence of an acute fast on ambulatory blood pressure and autonomic cardiovascular control.
Trial report in American journal of physiology. Regulatory, integrative and comparative physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07189637 (The Combined Effect of the Mediterranean Diet and Intermittent Fasting on Hypertension), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Combined Effect of the Mediterranean Diet and Intermittent Fasting on Hypertension
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Duration-dependent effects of water-only fasting on blood lipids: a systematic review, meta-analysis, and threshold meta-regression.Frontiers in nutrition · 2026Pooled it
- The Effects of Time-Restricted Feeding and Exercise on Cardiometabolic Health in Sedentary Older Adults: A Randomized Controlled Trial.Medicine and science in sports and exercise · 2026Trial
- Wrist-based wearable oscillometric blood pressure monitoring during Ramadan: a comparative study with standard devices.Frontiers in cardiovascular medicine · 2026Article
- Long-term fasting-induced parasympathetic and sympathetic autonomic nervous system modulation in a subgroup of the GENESIS study.International journal of obesity (2005) · 2025Article
- Observational
- Exploring the Impact of Intermittent Fasting on Vascular Function and the Immune System: A Narrative Review and Novel Perspective.Arteriosclerosis, thrombosis, and vascular biology · 2025Review
- N-of-1 health optimization: Digital monitoring of biomarker dynamics to gamify adherence to metabolic switching.PNAS nexus · 2024Article
- Acute fasting reduces tolerance to progressive central hypovolemia in humans.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence suggests that intermittent fasting improves cardiovascular health by reducing arterial blood pressure, but contributing mechanisms are unclear. The purpose of this study was to determine the influence of an acute fast on hemodynamics, muscle sympathetic nerve activity (MSNA), and autonomic control at rest and during an arterial pressure challenge. Twenty-five young normotensive volunteers were tested twice, in the fed and fasted (24 h) states (randomized). Twenty-four hour ambulatory blood pressure was measured before an autonomic function test, which consisted of a 10-min period of controlled breathing (CB) at 0.25 Hz followed by 3, 15-s Valsalva maneuvers (VMs). We recorded the ECG, beat-to-beat arterial pressure, and MSNA throughout the autonomic test. Vagal-cardiac modulation via heart rate variability (HRV) was assessed in both time and frequency domains, cardiovagal baroreflex sensitivity (cvBRS) was assessed with linear regression, and stroke volume was estimated from pulse contour. All fed versus fasted comparisons presented are different at
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.