Evidence map›Paper›PMID 35380304›Full record

ArticleCancer causes & control : CCC2022

An informatics infrastructure to catalyze cancer control research and practice.

Johnie Rose, Weichuan Dong, Uriel Kim, Joseph Hnath, Abby Statler, Paola Saroufim, Sunah Song, Mustafa Ascha, Harry Menegay, Ye Tian and 2 more

Abstract read
In one paragraph

Article in Cancer causes & control : CCC, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Gaps in artificial intelligence research for rural health in the United States: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Johnie RoseCase Western Reserve University Center for Community Health Integration, 11000 Cedar Ave., Ste. 402, Cleveland, OH, 44106-7136, USA. Johnie.rose@case.edu.ORCID http://orcid.org/0000-0001-7458-9303
Weichuan DongCase Comprehensive Cancer Center, Cleveland, OH, USA.
Uriel KimCase Western Reserve University Center for Community Health Integration, 11000 Cedar Ave., Ste. 402, Cleveland, OH, 44106-7136, USA.
Joseph HnathCase Western Reserve University Center for Community Health Integration, 11000 Cedar Ave., Ste. 402, Cleveland, OH, 44106-7136, USA.
Abby StatlerCase Comprehensive Cancer Center, Cleveland, OH, USA.
Paola SaroufimCleveland Institute for Computational Biology, Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Sunah SongCleveland Institute for Computational Biology, Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Mustafa AschaDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
Harry MenegayCleveland Institute for Computational Biology, Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Ye TianCleveland Institute for Computational Biology, Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Mark BenoCleveland Institute for Computational Biology, Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Siran M KoroukianCase Comprehensive Cancer Center, Cleveland, OH, USA.

Funding

TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Amar Desai · 1987 to 2026
$142.3M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
Transplant navigator interventuon to overcome barriers to kidney transplantionP60MD002265 · NIMHD · CASE WESTERN RESERVE UNIVERSITY · PI SEHGAL, ASHWINI · 2007 to 2016
$10.5M
Using Lay Health Advisors to Help African American Patients Address the Social Context of HypertensionU54MD002265 · NIMHD · CASE WESTERN RESERVE UNIVERSITY · PI SEHGAL, ASHWINI · 2017 to 2021
$7.1M
NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1 TR002548NCI NIH HHS P30 CA043703NIMHD NIH HHS P60 MD002265NIMHD NIH HHS U54 MD002265
6 · The paper itself

Abstract

purposeA disconnect often exists between those with the expertise to manage and analyze complex, multi-source data sets, and the clinical, social services, advocacy, and public health professionals who can pose the most relevant questions and best apply the answers. We describe development and implementation of a cancer informatics infrastructure aimed at broadening the usability of community cancer data to inform cancer control research and practice; and we share lessons learned.

methodsWe built a multi-level database known as The Ohio Cancer Assessment and Surveillance Engine (OH-CASE) to link data from Ohio's cancer registry with community data from the U.S. Census and other sources. Space-and place-based characteristics were assigned to individuals according to residential address. Stakeholder input informed development of an interface for generating queries based on geographic, demographic, and disease inputs and for outputting results aggregated at the state, county, municipality, or zip code levels.

resultsOH-CASE contains data on 791,786 cancer cases diagnosed from 1/1/2006 to 12/31/2018 across 88 Ohio counties containing 1215 municipalities and 1197 zip codes. Stakeholder feedback from cancer center community outreach teams, advocacy organizations, public health, and researchers suggests a broad range of uses of such multi-level data resources accessible via a user interface.

conclusionOH-CASE represents a prototype of a transportable model for curating and synthesizing data to understand cancer burden across communities. Beyond supporting collaborative research, this infrastructure can serve the clinical, social services, public health, and advocacy communities by enabling targeting of outreach, funding, and interventions to narrow cancer disparities.

Indexed as

Community-Institutional RelationsNeoplasmsDelivery of Health CareHumansInformaticsPublic HealthResearchCancer controlCancer preventionCancer registryCommunity-partnered researchDatabaseDisparities

Identifiers

PMID35380304
PMCPMC10865999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.