Evidence map›Paper›PMID 35380300›Full record

ReviewThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2022

COVID-19 and myocarditis: a review of literature.

Mohammed Ali, Haaris A Shiwani, Mohammed Y Elfaki, Moaz Hamid, Rebabonye Pharithi, Rene Kamgang, Christian BinounA Egom, Jean Louis Essame Oyono, Emmanuel Eroume-A Egom

Open access · diamondAbstract readReview
In one paragraph

Review in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
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  11. Fulminant Myocarditis with SARS-CoV-2 Infection: A Narrative Review from the Case Studies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Covid- 19 Vaccine-induced Myocarditis.Journal of community hospital internal medicine perspectives · 2023
    Article
  20. Myocarditis in COVID-19: a focus on the pediatric population.American journal of cardiovascular disease · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 5 countries.

Mohammed AliSchool of Medicine, The University of Manchester, Stopford Building, 99 Oxford Road, Manchester, M13 9PG, UK. mohammed.ali-24@student.manchester.ac.uk.ORCID http://orcid.org/0000-0003-3933-0333
Haaris A ShiwaniBurnley General Hospital, Burnley, UK.
Mohammed Y ElfakiSchool of Medicine, University College Dublin, Dublin, Ireland.
Moaz HamidBirmingham Midland Eye Centre, Birmingham, UK.
Rebabonye PharithiSt Vincent's University Hospital, Dublin, Ireland.
Rene KamgangSt Vincent's University Hospital, Dublin, Ireland.
Christian BinounA EgomFaculty of Medicine, University of N'Djamena, N'djamena, Chad.
Jean Louis Essame OyonoLaboratory of Endocrinology and Radioisotopes, Institute of Medical Research and Medicinal Plants Studies (IMPM), Yaoundé, Cameroon.
Emmanuel Eroume-A EgomLaboratory of Endocrinology and Radioisotopes, Institute of Medical Research and Medicinal Plants Studies (IMPM), Yaoundé, Cameroon.
Institut de Recherches Médicales et d’Etudes des Plantes Médicinales · CMSt. Vincent's University Hospital · IEBirmingham and Midland Eye Centre · GBBurnley General Teaching Hospital · GBUniversity College Dublin · IEUniversity of Manchester · GBUniversity of N'Djamena · TD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocarditis has been discovered to be a significant complication of coronavirus disease 2019 (COVID-19), a condition caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. COVID-19 myocarditis seems to have distinct inflammatory characteristics, which make it unique to other viral etiologies. The incidence of COVID-19 myocarditis is still not clear as a wide range of figures have been quoted in the literature; however, it seems that the risk of developing myocarditis increases with more severe infection. Furthermore, the administration of the mRNA COVID-19 vaccine has been associated with the development of myocarditis, particularly after the second dose. COVID-19 myocarditis has a wide variety of presentations, ranging from dyspnea and chest pain to acute heart failure and possibly death. It is important to catch any cases of myocarditis, particularly those presenting with fulminant myocarditis which can be characterized by signs of heart failure and arrythmias. Initial work up for suspected myocarditis should include serial troponins and electrocardiograms. If myocardial damage is detected in these tests, further screening should be carried out. Cardiac magnetic resonance imagining and endomyocardial biopsy are the most useful tests for myocarditis. Treatment for COVID-19 myocarditis is still controversial; however, the use of intravenous immunoglobulins and corticosteroids in combination may be effective, particularly in cases of fulminant myocarditis. Overall, the incidence of COVID-19 myocarditis requires further research, while the use of intravenous immunoglobulins and corticosteroids in conjunction requires large randomized controlled trials to determine their efficacy.

Indexed as

COVID-19Intravenous immunoglobulinsMyocarditisSARS-CoV-2Vaccine

Identifiers

PMID35380300
PMCPMC8980789
OpenAlexW4226093467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.