Evidence map›Paper›PMID 35380284›Full record

ArticleSurgical endoscopy2022

Reconstructing topography and extent of injury to the superior mesenteric artery plexus in right colectomy with extended D3 mesenterectomy: a composite multimodal 3-dimensional analysis.

Javier A Luzon, Yngve Thorsen, Liebert P Nogueira, Solveig N Andersen, Bjørn Edwin, Håvard J Haugen, Dejan Ignjatovic, Bojan V Stimec

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Javier A LuzonInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. jaluzon@gmail.com.ORCID http://orcid.org/0000-0002-6805-7076
Yngve ThorsenInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Liebert P NogueiraDepartment of Biomaterials, Institute of Clinical Dentistry, University of Oslo, Oslo, Norway.
Solveig N AndersenInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Bjørn EdwinInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Håvard J HaugenDepartment of Biomaterials, Institute of Clinical Dentistry, University of Oslo, Oslo, Norway.
Dejan IgnjatovicInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Bojan V StimecAnatomy Sector, Teaching Unit, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
University of Oslo · NOOslo University Hospital · NOUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuperior mesenteric artery plexus (SMAP) injury is reported to cause postoperative intractable diarrhea after pancreatic/colonic surgery with extended lymphadenectomy. This study aims to describe the SMAP microanatomy and extent of injury after right colectomy with extended D3 mesenterectomy for cancer.

methodsThree groups (I) anatomical dissection, (II) postmortem histology, and (III) surgical specimen histology were included. Nerve count and area were compared between groups II and III and paravascular sheath thickness between groups I and II. 3D models were generated through 3D histology, nanoCT scanning, and finally through 3D printing.

resultsA total of 21 specimens were included as follows: Group (I): 5 (3 females, 80-93 years), the SMAP is a complex mesh surrounding the superior mesenteric artery (SMA), branching out, following peripheral arteries and intertwining between them, (II): 7 (5 females, 71-86 years), nerve count: 53 ± 12.42 (38-68), and area: 1.84 ± 0.50 mm

conclusionSMAP surrounds the SMA and branches within the paravascular sheath, while bowel lymph nodes and vessels lie outside. Extent of SMAP injury on histological slides (transection only) was 48% nerve area and 59% nerve count. The 35°-55° inclination range of SMAP nerves possibly imply an even larger injury when plexus excision is performed (lymphadenectomy). Reasons for later improvement of bowel function in these patients can lie in the interarterial nerve fibers between SMA branches.

Indexed as

Colonic NeoplasmsLaparoscopyColectomyFemaleHumansLymph Node ExcisionLymph NodesMesenteric Artery, Superior3D imaging3D printingColon cancerHistologyNerve plexusSuperior mesenteric artery

Identifiers

PMID35380284
PMCPMC9485098
OpenAlexW4225723231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.