Evidence map›Paper›PMID 35380021›Full record

ArticleJournal of breast cancer2022

Ipsilateral Malignant Axillary Lymphadenopathy and Contralateral Reactive Lymph Nodes in a COVID-19 Vaccine Recipient With Breast Cancer.

Mehmet Emin Adin, Jennifer Wu, Edvin Isufi, Edison Tsui, Darko Pucar

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of breast cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mehmet Emin AdinDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, USA. Emin.adin@gmail.com.ORCID https://orcid.org/0000-0002-0070-9998
Jennifer WuDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, USA.ORCID https://orcid.org/0000-0001-9174-1127
Edvin IsufiDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, USA.ORCID https://orcid.org/0000-0001-9798-9019
Edison TsuiDepartment of Oncology, University of Massachusetts, Fall River, USA.ORCID https://orcid.org/0000-0003-0629-6212
Darko PucarDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, USA.ORCID https://orcid.org/0000-0001-6597-5149
Yale University · USNew England Center for Clinical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccine-related axillary nodal enlargement is a common benign condition that many mRNA vaccine receivers experience. However, a false attribution of axillary swelling to vaccination may result in delay in cancer care and potential disease progression, particularly in breast cancer patients presenting with ipsilateral axillary lymphadenopathy. We report the case of a 41-year-old pre-menopausal female who presented with suspicious axillary nodal enlargement and a right breast lump (triple-negative invasive ductal carcinoma) after recent administration of the second dose of Moderna mRNA coronavirus disease 2019 (COVID-19) vaccine. On imaging, bilateral axillary lymph nodes were detected. The ipsilateral right-sided node was proven to be metastatic, whereas contralateral nodes were related to a recent mRNA COVID-19 vaccination. Right-sided lymph node had intense uptake (maximum standardized uptake value [SUVmax] = 5), while the contralateral reactive nodes were mildly avid (SUVmax = 2.6). On magnetic resonance imaging, the right-sided node revealed asymmetric cortical thickening and marked cortical enhancement as opposed to normal-appearing left-sided nodes.

Indexed as

BreastCOVID-19LymphadenopathyNeoplasmsVaccines

Identifiers

PMID35380021
PMCPMC9065355
OpenAlexW4220829958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.