ArticleCommunications biology2022
Acquisition learning is stronger for aversive than appetitive events.
Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Aversive memory and extinction learning for noxious stimuli and aversive tastants in bumblebees.The Journal of experimental biology · 2026Article
- From Negentropy to Norms - A Gain-Based Theory of Agency: Kerdotism.Integrative psychological & behavioral science · 2026Article
- Divergent sensory transcriptomic profiles in positive and negative learning in Bicyclus Anynana butterflies.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Nocebo effects are stronger and more persistent than placebo effects in healthy individuals.eLife · 2025Article
- Review: Dopamine, Serotonin, and the Translational Neuroscience of Aggression in Autism Spectrum Disorder.JAACAP open · 2025Review
- Oviposition experience affects oviposition preference iniScience · 2024Article
- Neural underpinnings of preferential pain learning and the modulatory role of fear.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Prelimbic cortex ensembles promote appetitive learning-associated behavior.Learning & memory (Cold Spring Harbor, N.Y.)Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Appetitive and aversive learning are both key building blocks of adaptive behavior, yet knowledge regarding their differences is sparse. Using a capsaicin heat pain model in 36 healthy participants, this study directly compared the acquisition and extinction of conditioned stimuli (CS) predicting pain exacerbation and relief. Valence ratings show stronger acquisition during aversive compared to appetitive learning, but no differences in extinction. Skin conductance responses and contingency ratings confirmed these results. Findings were unrelated to individual differences in pain sensitivity or psychological factors. Our results support the notion of an evolutionarily hardwired preponderance to acquire aversive rather than appetitive cues as is protective for acute aversive states such as pain but may contribute to the development and maintenance of clinical conditions such as chronic pain, depression or anxiety disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.