Evidence map›Paper›PMID 35379812›Full record

ArticleScientific reports2022

Proposal of a population wide genome-based testing for Covid-19.

Hans Lehrach, Jon Curtis, Bodo Lange, Lesley A Ogilvie, Richard Gauss, Christoph Steininger, Erhard Scholz, Matthias Kreck

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Prospective, clinical comparison of self-collected throat-bilateral nares swabs and saline gargle compared to health care provider collected nasopharyngeal swabs among symptomatic outpatients with potential SARS-CoV-2 infection.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Hans LehrachAlacris Theranostics GmbH, Berlin, Germany. lehrach@molgen.mpg.de.
Jon CurtisAlacris Theranostics GmbH, Berlin, Germany.
Bodo LangeAlacris Theranostics GmbH, Berlin, Germany.
Lesley A OgilvieAlacris Theranostics GmbH, Berlin, Germany.
Richard GaussState Sanitary Directorate, City Government, Vienna, Austria.
Christoph SteiningerDepartment of Medicine I, Division of Infectious Diseases, Medical University of Vienna, Vienna, Austria.
Erhard ScholzUniversity of Wuppertal, Wuppertal, Germany.
Matthias KreckUniversity of Bonn, Bonn, Germany.
Alacris (Germany) · DEGovernment of Lower Austria · ATMedical University of Vienna · ATUniversity of Bonn · DEUniversity of Wuppertal · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our lives (and deaths) have by now been dominated for two years by COVID-19, a pandemic that has caused hundreds of millions of disease cases, millions of deaths, trillions in economic costs, and major restrictions on our freedom. Here we suggest a novel tool for controlling the COVID-19 pandemic. The key element is a method for a population-scale PCR-based testing, applied on a systematic and repeated basis. For this we have developed a low cost, highly sensitive virus-genome-based test. Using Germany as an example, we demonstrate by using a mathematical model, how useful this strategy could have been in controlling the pandemic. We show using real-world examples how this might be implemented on a mass scale and discuss the feasibility of this approach.

Indexed as

COVID-19Influenza, HumanCOVID-19 TestingHumansModels, TheoreticalPandemics

Identifiers

PMID35379812
PMCPMC8978767
OpenAlexW4226116276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.