Evidence map›Paper›PMID 35379799›Full record

ArticleCell death & disease2022

Removal of BFL-1 sensitises some melanoma cells to killing by BH3 mimetic drugs.

Lahiru Gangoda, Robyn L Schenk, Lin Tai, Pacman Szeto, Jen G Cheung, Andreas Strasser, Guillaume Lessene, Mark Shackleton, Marco J Herold

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lahiru GangodaThe Walter and Eliza Hall Institute of Medical Research (WEHI), 1G Royal Parade, Parkville, Melbourne, VIC, 3052, Australia.
Robyn L SchenkThe Walter and Eliza Hall Institute of Medical Research (WEHI), 1G Royal Parade, Parkville, Melbourne, VIC, 3052, Australia.
Lin TaiThe Walter and Eliza Hall Institute of Medical Research (WEHI), 1G Royal Parade, Parkville, Melbourne, VIC, 3052, Australia.
Pacman SzetoDepartment of Oncology, Alfred Health, Melbourne, VIC, 3004, Australia.ORCID 0000-0002-6159-9913
Jen G CheungDepartment of Oncology, Alfred Health, Melbourne, VIC, 3004, Australia.
Andreas StrasserThe Walter and Eliza Hall Institute of Medical Research (WEHI), 1G Royal Parade, Parkville, Melbourne, VIC, 3052, Australia.ORCID 0000-0002-5020-4891
Guillaume LesseneThe Walter and Eliza Hall Institute of Medical Research (WEHI), 1G Royal Parade, Parkville, Melbourne, VIC, 3052, Australia.ORCID 0000-0002-1193-8147
Mark ShackletonDepartment of Oncology, Alfred Health, Melbourne, VIC, 3004, Australia.ORCID 0000-0002-7673-4655
Marco J HeroldThe Walter and Eliza Hall Institute of Medical Research (WEHI), 1G Royal Parade, Parkville, Melbourne, VIC, 3052, Australia. herold@wehi.edu.au.ORCID 0000-0001-7539-7581

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MelanomaProto-Oncogene Proteins c-bcl-2ApoptosisCell Line, TumorHumansMethylcelluloseMyeloid Cell Leukemia Sequence 1 ProteinMethylcelluloseMyeloid Cell Leukemia Sequence 1 ProteinProto-Oncogene Proteins c-bcl-2

Identifiers

PMID35379799
PMCPMC8980089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.