Evidence map›Paper›PMID 35379749›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

RORγt-Expressing Pathogenic CD4

Michel Edwar Mickael, Suniti Bhaumik, Ayanabha Chakraborti, Alan A Umfress, Thomas van Groen, Matthew Macaluso, John Totenhagen, Anna G Sorace, James A Bibb, David G Standaert and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

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  16. Upregulation of Inflammatory Mediators in Peripheral Blood CD40International journal of molecular sciences · 2023
    Article
  17. Article
  18. Article
  19. The Journey of Cancer Cells to the Brain: Challenges and Opportunities.International journal of molecular sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Michel Edwar MickaelDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0002-4186-4900
Suniti BhaumikDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0003-1434-6929
Ayanabha ChakrabortiDepartment of Surgery, Neuroscience, and Neurology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL.
Alan A UmfressDepartment of Surgery, Neuroscience, and Neurology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0002-5182-0258
Thomas van GroenDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0002-1861-7530
Matthew MacalusoDepartment of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL.
John TotenhagenDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Anna G SoraceDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0002-3640-3966
James A BibbDepartment of Surgery, Neuroscience, and Neurology, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL.
David G StandaertDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0003-2921-8348
Rajatava BasuDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL; rajatavabasu@uabmc.edu.ORCID 0000-0003-4029-8043
University of Alabama at Birmingham · US

Funding

Yale/NIDA Neuroproteomics Research CenterP30DA018343 · NIDA · YALE UNIVERSITY · PI ANGUS C. NAIRN, Kenneth Robert WILLIAMS · 2004 to 2026
$37.1M
Project 3: LRRK2 mediated macrophage responses in PDP50NS108675 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STANDAERT, DAVID G. · 2018 to 2022
$9.9M
UAB Research Training Program in Neurobiology of Cognition and Cognitive DisordersT32NS061788 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Farah Dominique Lubin · 2008 to 2026
$4.5M
PERIPHERAL INFLAMMATION AND STRESS DRIVE VENTRAL STRIATAL MALADAPTATIONSR01MH126948 · NIMH · UNIVERSITY OF ARIZONA · PI BIBB, JAMES A · 2021 to 2025
$2.5M
The Regulation of Dopamine Neurotransmission by CDK5R01MH079710 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI BIBB, JAMES A · 2008 to 2011
$1.7M
Excitatory and Metabotopic Regulation of PKA in Stress and ResilienceR01MH116896 · NIMH · UNIVERSITY OF ARIZONA · PI BIBB, JAMES A · 2019 to 2022
$1.5M
Excitatory and Metabotopic Regulation of PKA in Stress and ResilienceR56MH116896 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BIBB, JAMES A · 2018 to 2018
$371k
NIDA NIH HHS P30 DA018343NIMH NIH HHS R01 MH079710NIMH NIH HHS R01 MH116896NIMH NIH HHS R01 MH126948NIMH NIH HHS R56 MH116896NINDS NIH HHS P50 NS108675NINDS NIH HHS T32 NS061788
6 · The paper itself

Abstract

Neurobehavioral disorders and brain abnormalities have been extensively reported in both Crohn's disease and ulcerative colitis patients. However, the mechanism causing neuropathological disorders in inflammatory bowel disease patients remains unknown. Studies have linked the Th17 subset of CD4

Indexed as

ColitisEncephalitisAnimalsCarrier ProteinsCD4-Positive T-LymphocytesDisease Models, AnimalGliosisHomeodomain ProteinsHumansInflammationMiceMice, Inbred C57BLNuclear Receptor Subfamily 1, Group F, Member 3Receptors, Retinoic AcidTh17 CellsCarrier ProteinsHomeodomain ProteinsNuclear Receptor Subfamily 1, Group F, Member 3Receptors, Retinoic AcidRorc protein, mouse

Identifiers

PMID35379749
PMCPMC10103644
OpenAlexW4224035493

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.