Evidence map›Paper›PMID 35379621›Full record

ArticleBMJ open2022

Gatekeeper training for vendors to reduce pesticide self-poisoning in rural South Asia: a study protocol for a stepped-wedge cluster randomised controlled trial.

Manjula Weerasinghe, Melissa Pearson, Nicholas Turner, Chris Metcalfe, David J Gunnell, Suneth Agampodi, Keith Hawton, Thilini Agampodi, Matthew Miller, Shaluka Jayamanne and 13 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 10 institutions in 5 countries.

Manjula WeerasingheCentre for Pesticide Suicide Prevention, and Pharmacology, Toxicology and Therapeutics, Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK manjugaya@yahoo.com.ORCID 0000-0002-6105-7989
Melissa PearsonCentre for Pesticide Suicide Prevention, and Pharmacology, Toxicology and Therapeutics, Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Nicholas TurnerPopulation Health Sciences, University of Bristol, Bristol, UK.
Chris MetcalfePopulation Health Sciences, University of Bristol, Bristol, UK.ORCID 0000-0001-8318-8907
David J GunnellPopulation Health Sciences, University of Bristol, Bristol, UK.
Suneth AgampodiDepartment of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Anuradhapura, Sri Lanka.
Keith HawtonCentre for Suicide Research, Department of Psychiatry, University of Oxford, Oxford, UK.ORCID 0000-0003-4985-5715
Thilini AgampodiDepartment of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Anuradhapura, Sri Lanka.
Matthew MillerNortheastern University, 360 Huntington Avenue, Boston, Massachusetts, USA.
Shaluka JayamanneDepartment of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Simon ParkerEdinburgh Medical School, University of Edinburgh, Edinburgh, UK.
Jayakody Arachchige SumithOffice of the Registrar of Pesticides, Peradeniya, Sri Lanka.
Ayanthi KarunarathneTertiary Care Services, Ministry of Health, Colombo, Sri Lanka.
Kalpani DissanayakaSouth Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Sandamali RajapakshaSouth Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Dilani RodrigoSouth Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Dissanayake AbeysingheSouth Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Chathuranga PiyasenaSouth Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Rajaratnam KanapathySouth Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Sundaresan ThedchanamoorthyDepartment of Clinical Sciences, Faculty of Health Care Sciences, Eastern University, Batticaloa, Sri Lanka.
Lizell Bustamante MadsenGlobal Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Flemming KonradsenGlobal Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Michael EddlestonCentre for Pesticide Suicide Prevention, and Pharmacology, Toxicology and Therapeutics, Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
University of Peradeniya · LKRajarata University of Sri Lanka · LKUniversity of Bristol · GBUniversity of Copenhagen · DKUniversity of Edinburgh · GBEastern University, Sri Lanka · LKNortheastern University · USThe University of Sydney · AUUniversity of Kelaniya · LKUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPesticide self-poisoning kills an estimated 110 000-168 000 people worldwide annually. Data from South Asia indicate that in 15%-20% of attempted suicides and 30%-50% of completed suicides involving pesticides these are purchased shortly beforehand for this purpose. Individuals who are intoxicated with alcohol and/or non-farmers represent 72% of such customers. We have developed a 'gatekeeper' training programme for vendors to enable them to identify individuals at high risk of self-poisoning (gatekeeper function) and prevent such individuals from accessing pesticides (means restriction). The primary aim of the study is to evaluate the effectiveness of the gatekeeper intervention in preventing pesticide self-poisoning in Sri Lanka. Other aims are to identify method substitution and to assess the cost and cost-effectiveness of the intervention. METHODS AND ANALYSIS: A stepped-wedge cluster randomised trial of a gatekeeper intervention is being conducted in rural Sri Lanka with a population of approximately 2.7 million. The gatekeeper intervention is being introduced into 70 administrative divisions in random order at each of 30 steps over a 40-month period. The primary outcome is the number of pesticide self-poisoning cases identified from surveillance of hospitals and police stations. Secondary outcomes include: number of self-poisoning cases using pesticides purchased within the previous 24 hours, total number of all forms of self-harm and suicides. Intervention effectiveness will be estimated by comparing outcome measures between the pretraining and post-training periods across the divisions in the study area. The original study protocol has been adapted as necessary in light of the impact of the COVID-19. ETHICS AND DISSEMINATION: The Ethical Review Committee of the Faculty of Medicine and Allied Sciences, Rajarata University, Sri Lanka (ERC/2018/30), and the ACCORD Medical Research Ethics Committee, Edinburgh University (18-HV-053) approved the study. Results will be disseminated in scientific peer-reviewed journals. TRIAL REGISTRATION NUMBER: SLCTR/2019/006, U1111-1220-8046.

Indexed as

COVID-19PesticidesCommerceHumansRandomized Controlled Trials as TopicRural PopulationSri LankaPesticidespublic healthsuicide & self-harmtoxicology

Identifiers

PMID35379621
PMCPMC8981379
OpenAlexW4224327277

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.