Evidence map›Paper›PMID 35379372›Full record

ArticlePrehospital and disaster medicine2022

Novel Negative Pressure Procedural Tent Reduces Aerosolized Particles in a Simulated Prehospital Setting.

Nathaniel Hunt, Spencer Masiewicz, Logan Herbert, Benjamin Bassin, Christine Brent, Nathan L Haas, Mohamad Hakam Tiba, Jon Lillemoen, Mark J Lowell, Isabel Lott and 3 more

Abstract read
In one paragraph

Article in Prehospital and disaster medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nathaniel HuntDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.ORCID https://orcid.org/0000-0003-3600-1817
Spencer MasiewiczDepartment of Emergency Medicine, Northeast Georgia Medical Center, Gainesville, Georgia USA.
Logan HerbertDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.
Benjamin BassinDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.
Christine BrentDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.
Nathan L HaasDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.
Mohamad Hakam TibaDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.
Jon LillemoenUniversity of Michigan Environment, Health and Safety, Ann Arbor, MichiganUSA.
Mark J LowellDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.
Isabel LottUniversity of Michigan Medical School, Ann Arbor, MichiganUSA.
Matthew BasingerDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.
Graham SmithDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.
Kevin R WardDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MichiganUSA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveThe coronavirus disease 2019 (COVID-19) pandemic has challenged the ability of Emergency Medical Services (EMS) providers to maintain personal safety during the treatment and transport of patients potentially infected. Increased rates of COVID-19 infection in EMS providers after patient care exposure, and notably after performing aerosol-generating procedures (AGPs), have been reported. With an already strained workforce seeing rising call volumes and increased risk for AGP-requiring patient presentations, development of novel devices for the protection of EMS providers is of great importance.Based on the concept of a negative pressure room, the AerosolVE BioDome is designed to encapsulate the patient and contain aerosolized infectious particles produced during AGPs, making the cabin of an EMS vehicle safer for providers. The objective of this study was to determine the efficacy and safety of the tent in mitigating simulated infectious particle spread in varied EMS transport platforms during AGP utilization.

methodsFifteen healthy volunteers were enrolled and distributed amongst three EMS vehicles: a ground ambulance, an aeromedical-configured helicopter, and an aeromedical-configured jet. Sodium chloride particles were used to simulate infectious particles and particle counts were obtained in numerous locations close to the tent and around the patient compartment. Counts near the tent were compared to ambient air with and without use of AGPs (non-rebreather mask, continuous positive airway pressure [CPAP] mask, and high-flow nasal cannula [HFNC]).

resultsFor all transport platforms, with the tent fan off, the particle generator alone, and with all AGPs produced particle counts inside the tent significantly higher than ambient particle counts (P <.0001). With the tent fan powered on, particle counts near the tent, where EMS providers are expected to be located, showed no significant elevation compared to baseline ambient particle counts during the use of the particle generator alone or with use of any of the AGPs across all transport platforms.

conclusionDevelopment of devices to improve safety for EMS providers to allow for use of all available therapies to treat patients while reducing risk of communicable respiratory disease transmission is of paramount importance. The AerosolVE BioDome demonstrated efficacy in creating a negative pressure environment and workspace around the patient and provided significant filtration of simulated respiratory droplets, thus making the confined space of transport vehicles potentially safer for EMS personnel.

Indexed as

COVID-19Emergency Medical ServicesAerosolized Particles and DropletsAerosolsHumansPandemicsSARS-CoV-2Aerosolized Particles and DropletsAerosolsaerosol-generating proceduresCOVID-19mitigationnegative pressure tentprehospital

Identifiers

PMID35379372
PMCPMC9118043

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.