ArticleEuropean journal of medical research2022
Serum levels of vitamin D, retinol, zinc, and CRP in relation to obesity among children and adolescents.
Article in European journal of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Overnutrition is a risk factor for iron, but not for zinc or vitamin A deficiency in children and young people: a systematic review and meta-analysis.BMJ global health · 2024Pooled it
- The relationships between fat-soluble vitamin deficiency and childhood obesity risk.Frontiers in pediatrics · 2026Article
- Plasma vitamin D levels in obese individuals with peptic ulcer disease from NAHSIT databank of Taiwan.Scientific reports · 2025Article
- Relationship between C-reactive protein-albumin ratio and prognosis in pediatric patients with severe burns.PloS one · 2025Article
- Serum vitamin D and obesity among US adolescents, NHANES 2011-2018.Frontiers in pediatrics · 2024Article
- Vitamin A Nutritional Status of Urban Lactating Chinese Women and Its Associated Factors.Nutrients · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe aim of this study was to examine the possible association between serum micronutrients (vitamin D, retinol, zinc), C-reactive protein (CRP), and obesity among children and adolescents.
methodsWeight and height were measured and serum 25-hydroxy vitamin D, serum retinol, serum zinc, and CRP were measured in 2818 children and adolescents (6-17 years of age), and the data of 10 investigation sites in Zhejiang Province were used. The difference of micronutrients (vitamin D, retinol, zinc) and CRP among different nutritional status were explored by ANOVA and Chi-square test. The associated factors of micronutrients and CRP of overweight and obesity were explored by multifactor analysis.
resultsThere were significant differences between male students and female students on BMI, 25(OH)D3, and CRP, and there were significant differences between children and adolescents and between students living in urban area and rural area on BMI, 25(OH)D3, retinol, and zinc(t > 1.96, p < 0.05). There were significant differences on 25(OH)D3 and CRP level among children and adolescents with different nutritional conditions (F = 2.612, 15.022, p < 0.05). In multifactor analysis, we found that female [odds ratio (OR) = 0.68, 95% CI 0.49-0.81], living in rural area (OR = 0.68, 95% CI 0.56-0.82), age (OR = 0.95, 95% CI 0.92-0.98), high CRP concentration (OR = 1.08, 95% CI 1.04-1.12) and appropriate retinol level (OR = 1.32, 95% CI 1.09-1.59) were associated with obesity compared to low/normal BMI.
conclusionGender, living area, age, CRP concentration, and vitamin A status were associated with children and adolescents with overweight and obesity compared to low/normal BMI. More attention in the intervention of overweight and obesity should be paid to boys living in urban areas, and high serum concentration of CRP should also be concerned.
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