Evidence map›Paper›PMID 35379312›Full record

ArticleCritical care (London, England)2022

Intensive care-related loss of quality of life and autonomy at 6 months post-discharge: Does COVID-19 really make things worse?

Fabrice Thiolliere, Claire Falandry, Bernard Allaouchiche, Victor Geoffray, Laurent Bitker, Jean Reignier, Paul Abraham, Stephanie Malaquin, Baptiste Balança, Hélène Boyer and 6 more

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Global prevalence of post-COVID-19 condition: a systematic review and meta-analysis of prospective evidence.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025
    Pooled it
  3. Trial
  4. Article
  5. Observational
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Fabrice ThiolliereDépartement d'Anesthésie Réanimation, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France.
Claire FalandryHospices Civils de Lyon, Geriatrics Unit, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.
Bernard AllaouchicheDépartement d'Anesthésie Réanimation, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France.
Victor GeoffrayDépartement d'Anesthésie Réanimation, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France.
Laurent BitkerService de Médecine Intensive - Réanimation, Hôpital de La Croix Rousse, Hospices Civils de Lyon, Lyon, France.
Jean ReignierService de Médecine Intensive Réanimation, CHU de Nantes, Nantes, France.
Paul AbrahamService d'Anesthésie-Réanimation, Hôpital Édouard Herriot, 69008, Hospices civils de LyonLyon, France.
Stephanie MalaquinRéanimation chirurgicale, CHU amiens, Lyon, France.
Baptiste BalançaHospices Civils de Lyon, service d'anesthésie réanimation neurologique, Hôpital Pierre Wertheimer, département d'anesthésie reanimation, 59 Boulevard Pinel, 69500, Bron, France.
Hélène BoyerDirection de la Recherche en Santé, Hospices Civils de Lyon, Lyon, France.
Philippe SeguinRéanimation chirurgicale. CHU Rennes, 2 rue Henri Le Guilloux, 35000, Rennes, France.
Céline GuichonDépartement d'anesthésie et réanimation chirurgicale, hôpital Croix Rousse, Hospices Civils de Lyon, Lyon, France.
Marie SimonMédecine Intensive - Réanimation- Hôpital Edouard Herriot, 1 place d'Arsonval, 69003, Lyon, France.
Arnaud FriggeriDépartement d'Anesthésie Réanimation, Centre Hospitalier Lyon Sud Hospices Civils de Lyon, Pierre-Bénite, France.
Charles-Hervé VacheronDépartement d'Anesthésie Réanimation, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France. charles-herve.vacheron@chu-lyon.fr.ORCID 0000-0003-1575-5847
AZUREA Study Group
Université Claude Bernard Lyon 1 · FRCentre Hospitalier Universitaire de Nantes · FRHospices Civils de Lyon · FRCentre Hospitalier Universitaire Amiens-Picardie · FRCentre Hospitalier Universitaire de Rennes · FRCentre de Recherche en Neurosciences de Lyon · FRHôpital Edouard Herriot · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare old patients hospitalized in ICU for respiratory distress due to COVID-19 with old patients hospitalized in ICU for a non-COVID-19-related reason in terms of autonomy and quality of life.

designComparison of two prospective multi-centric studies.

settingThis study was based on two prospective multi-centric studies, the Senior-COVID-Rea cohort (COVID-19-diagnosed ICU-admitted patients aged over 60) and the FRAGIREA cohort (ICU-admitted patients aged over 70). PATIENTS: We included herein the patients from both cohorts who had been evaluated at day 180 after admission (ADL score and quality of life).

interventionsNone. MEASUREMENTS AND MAIN

resultsA total of 93 COVID-19 patients and 185 control-ICU patients were included. Both groups were not balanced on age, body mass index, mechanical ventilation, length of ICU stay, and ADL and SAPS II scores. We modeled with ordered logistic regression the influence of COVID-19 on the quality of life and the ADL score. After adjustment on these factors, we observed COVID-19 patients were less likely to have a loss of usual activities (aOR [95% CI] 0.47 [0.23; 0.94]), a loss of mobility (aOR [95% CI] 0.30 [0.14; 0.63]), and a loss of ADL score (aOR [95% CI] 0.30 [0.14; 0.63]). On day 180, 52 (56%) COVID-19 patients presented signs of dyspnea, 37 (40%) still used analgesics, 17 (18%) used anxiolytics, and 14 (13%) used antidepressant.

conclusionsCOVID-19-related ICU stay was not associated with a lower quality of life or lower autonomy compared to non-COVID-19-related ICU stay.

Indexed as

COVID-19Quality of LifeAftercareAgedCritical CareHumansIntensive Care UnitsOutcome Assessment, Health CarePatient DischargeProspective StudiesAutonomyCOVID-19Quality of life

Identifiers

PMID35379312
PMCPMC8978758
OpenAlexW4225636549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.