SynthesisBMC pulmonary medicine2022
Predictors of mortality in chronic obstructive pulmonary disease: a systematic review and meta-analysis.
Synthesis in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Pooled it
- Frailty and its influence on mortality and morbidity in COPD: A Systematic Review and Meta-Analysis.Internal and emergency medicine · 2023Pooled it
- Article
- Two distinct healthcare utilisation trajectories prior to a COPD diagnosis in a multi-ethnic Asian population: a comparison of transient and chronic users.BMJ open respiratory research · 2026Article
- Prognostic models for mortality and hospitalisation risk in a contemporary Australian chronic obstructive pulmonary disease cohort.Respiratory research · 2026Article
- Unmet Needs and New Opportunities in Chronic Obstructive Pulmonary Disease in Italy: A Narrative Review with Insights from the GULP Study.International journal of chronic obstructive pulmonary disease · 2026Review
- Development and Internal Validation of a Multivariable Prognostic Model for in-Hospital Mortality in Critically Ill Patients with Acute Exacerbation of COPD.International journal of chronic obstructive pulmonary disease · 2026Observational
- Predictors of mortality and hospitalised exacerbations in obstructive airway diseases.ERJ open research · 2025Article
- Article
- Resilience and health-related quality of life in patients with pulmonary diseases receiving ambulatory oxygen therapy - 24-month follow-up results.BMC pulmonary medicine · 2025Observational
- Predictive Value of CCQ and its Subdomains for Hospitalized Exacerbations in Chronic Obstructive Pulmonary Disease: A 3-Year Observational Prospective Study.Journal of general internal medicine · 2025Observational
- Residential greenness and chronic obstructive pulmonary disease in a large cohort in southern China: Potential causal links, risk trajectories, and mediation pathways.Journal of advanced research · 2025Article
- Chronic obstructive pulmonary disease: A narrative synthesis of its hallmarks for palliative care clinicians.European journal of internal medicine · 2025Review
- CT-derived functional imaging biomarkers combined with FEV1 for predicting 10-year all-cause mortality in COPDGene cohort.npj biomedical innovations · 2025Article
- Major Adverse Cardiovascular Events and Cause-Specific Mortality After Hospitalisation in COPD.International journal of chronic obstructive pulmonary disease · 2025Article
- Predictors of Clinical Stability and Mortality in COPD: A Longitudinal Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Development and validation of a novel AI-derived index for predicting COPD medical costs in clinical practice.Computational and structural biotechnology journal · 2025Article
- Temporal trends, gender, and ethnoracial disparities in mortality from pulmonary emphysema: A retrospective nationwide analysis.Medicine · 2024Article
- Advance care planning in patients with respiratory failure.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- The PROgnostic ModEl for chronic lung disease (PRO-MEL): development and temporal validation.BMC pulmonary medicine · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundBetter insight in patients' prognosis can help physicians to timely initiate advance care planning (ACP) discussions with patients with chronic obstructive pulmonary disease (COPD). We aimed to identify predictors of mortality.
methodsWe systematically searched databases Embase, PubMed, MEDLINE, Web of Science, and Cochrane Central in April 2020. Papers reporting on predictors or prognostic models for mortality at 3 months and up to 24 months were assessed on risk-of-bias. We performed a meta-analysis with a fixed or random-effects model, and evaluated the discriminative ability of multivariable prognostic models.
resultsWe included 42 studies (49-418,251 patients); 18 studies were included in the meta-analysis. Significant predictors of mortality within 3-24 months in the random-effects model were: previous hospitalization for acute exacerbation (hazard ratio [HR] 1.97; 95% confidence interval [CI] 1.32-2.95), hospital readmission within 30 days (HR 5.01; 95% CI 2.16-11.63), cardiovascular comorbidity (HR 1.89; 95% CI 1.25-2.87), age (HR 1.48; 95% CI 1.38-1.59), male sex (HR 1.68; 95% CI 1.38-1.59), and long-term oxygen therapy (HR 1.74; 95% CI 1.10-2.73). Nineteen previously developed multicomponent prognostic models, as examined in 11 studies, mostly had moderate discriminate ability.
conclusionIdentified predictors of mortality may aid physicians in selecting COPD patients who may benefit from ACP. However, better discriminative ability of prognostic models or development of a new prognostic model is needed for further large-scale implementation. REGISTRATION: PROSPERO (CRD42016038494), https://www.crd.york.ac.uk/prospero/ .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.